DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5028 and IDH-III

DIOPT Version :9

Sequence 1:	NP_001097922.1	Gene:	CG5028 / 43102	FlyBaseID:	FBgn0039358	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_195290.1	Gene:	IDH-III / 829717	AraportID:	AT4G35650	Length:	368	Species:	Arabidopsis thaliana

Alignment Length:	354	Identity:	153/354 - (43%)
Similarity:	220/354 - (62%)	Gaps:	12/354 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SALQKKVTGTDIPSAQYGGRHAVTMLPGGGIGPELMGYVREIFRYCGAPIDFEVIDIDPSTEGN- 101
            ::|.:.:  |.:|....|....||::||.||||.:.|.|.::.....||:.||..::    .||
plant    21 TSLSRSI--TYMPRPGDGAPRTVTLIPGDGIGPLVTGAVEQVMEAMHAPVHFERYEV----LGNM 79

  Fly   102 -DDLDYAITSIKRNGVALKGNIETKSQSLTEVSRNVAIRNELDLYVNVVHCKSYPGIPARHHDID 165
             ...:..|.|:|||.|.|||.:.|....... |.|:.:|.|||::.::|:|.:.||:..||.::|
plant    80 RKVPEEVIESVKRNKVCLKGGLATPVGGGVS-SLNMQLRKELDIFASLVNCINVPGLVTRHENVD 143

  Fly   166 VVLIRQNTDGEYAMLEHESVPGIVESMKVVTVENAERVARYAFEFARQNNRKKVTTIHKANIMKL 230
            :|:||:||:|||:.||||.|||:|||:||:|...:||:||||||:|..|||||||.:||||||||
plant   144 IVVIRENTEGEYSGLEHEVVPGVVESLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKL 208

  Fly   231 SDGLFLEVANRVHKDYPELEHNNMIIDNTCMQSVSNPHQFDVMNMTNLYGTIVSNVLCGLMGGAG 295
            :||||||....|.|.|..:.:|.:|:||.|||.|:.|.|||||...||||.:::|...|:.||.|
plant   209 ADGLFLESCREVAKHYSGITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLIANTAAGIAGGTG 273

  Fly   296 LISGRNYGDHYAIFEPGTR--NTGT-AIAGKNIANPVAMISASIDMLNHLGHKEHANVIQEAVYQ 357
            ::.|.|.|..:||||.|..  |.|. .:..:..|||||::.:|..||.||.....|:.::.||.|
plant   274 VMPGGNVGAEHAIFEQGASAGNVGNDKMVEQKKANPVALLLSSAMMLRHLRFPTFADRLETAVKQ 338

  Fly   358 TIVNDAIRTPDIGGTNSSTDVVENILKIL 386
            .|.....||.|:||..::.:||:.::..|
plant   339 VIKEGKYRTKDLGGDCTTQEVVDAVIAAL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5028	NP_001097922.1	mito_nad_idh	55..386	CDD:272942	149/335 (44%)
IDH-III	NP_195290.1	PLN00123	8..368	CDD:215065	153/354 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55803
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D868374at2759
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101342
Panther	1	1.100	-	-	O	PTHR11835
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.790