DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5028 and idh3b

DIOPT Version :9

Sequence 1:	NP_001097922.1	Gene:	CG5028 / 43102	FlyBaseID:	FBgn0039358	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	XP_017208256.1	Gene:	idh3b / 415247	ZFINID:	ZDB-GENE-040625-174	Length:	386	Species:	Danio rerio

Alignment Length:	375	Identity:	158/375 - (42%)
Similarity:	239/375 - (63%)	Gaps:	7/375 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RGYPLLVTKEKT----EDVAHTKSALQKKVTGTDIPSAQYGGRHAVTMLPGGGIGPELMGYVREI 79
            ||..|.:.|..|    :.:.....:|.......:.|.|:......|||:||.|:|||||..|:|:
Zfish     7 RGSVLTLAKGLTGVRLQPLCARSLSLTSSQNVPESPPARADSTFKVTMVPGDGVGPELMTAVKEV 71

  Fly    80 FRYCGAPIDFEVIDID--PSTEGNDDLDYAITSIKRNGVALKGNIETKSQSLTEV-SRNVAIRNE 141
            |:....|::||...:.  .:....:.|:..::|:|.|.||:||.|.|..:...|: |..:.:|.:
Zfish    72 FKAADVPVEFEEFHLSEVQNMASEEKLNEVLSSMKNNRVAIKGKIHTPMEYKGELASYEMRLRRK 136

  Fly   142 LDLYVNVVHCKSYPGIPARHHDIDVVLIRQNTDGEYAMLEHESVPGIVESMKVVTVENAERVARY 206
            |||:.||||.||.||...||:::|:|:||:.|:|||:.||||||.|:||.:|::|.|.:.|:|::
Zfish   137 LDLFANVVHVKSLPGYSTRHNNLDLVIIREQTEGEYSSLEHESVAGVVECLKIITREKSRRIAKF 201

  Fly   207 AFEFARQNNRKKVTTIHKANIMKLSDGLFLEVANRVHKDYPELEHNNMIIDNTCMQSVSNPHQFD 271
            ||::|.:..|.|||.:||||||||.|||||:....|.:.||::::.|:||||.|||.|.||:|||
Zfish   202 AFDYATKKGRSKVTAVHKANIMKLGDGLFLQSCAEVAELYPKIKYENVIIDNCCMQLVQNPYQFD 266

  Fly   272 VMNMTNLYGTIVSNVLCGLMGGAGLISGRNYGDHYAIFEPGTRNTGTAIAGKNIANPVAMISASI 336
            |:.|.||||.|:.|:..||:||||::.|.:|...||:||.|.|:......|:|||||.||:.::.
Zfish   267 VLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSAS 331

  Fly   337 DMLNHLGHKEHANVIQEAVYQTIVNDAIRTPDIGGTNSSTDVVENILKIL 386
            :||.||..:.|:|::.|||.:.|....:||.|:||.:::.|.:..|:..|
Zfish   332 NMLKHLNLEYHSNMVSEAVKKVIKQGKVRTRDLGGYSTTGDFIRAIVASL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5028	NP_001097922.1	mito_nad_idh	55..386	CDD:272942	149/333 (45%)
idh3b	XP_017208256.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101342
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R585
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.760