Protein Alignment Idh3g and IDH3G

DIOPT Version :10

• Sequence 1: NP_651416.1
• Gene: Idh3g / 43102
• FlyBaseID: FBgn0039358
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_004126.1
• Gene: IDH3G / 3421
• HGNCID: 5386
• Length: 393
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 180/337 - (53%)
• Similarity: 246/337 - (72%)
• Gaps: 4/337 - (1%)

  Fly    50 PSAQYGGRHAVTMLPGGGIGPELMGYVREIFRYCGAPIDFEVIDIDPSTEGNDDLDYAITSIKRN 114
            |||:|||||.|||:||.|||||||.:|:.:||:...|:|||.:.:. |....:|:..||.:|:||
Human    47 PSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVS-SNADEEDIRNAIMAIRRN 110

  Fly   115 GVALKGNIETKSQSL--TEVSRNVAIRNELDLYVNVVHCKSYPGIPARHHDIDVVLIRQNTDGEY 177
            .||||||||| :.:|  :..|||..:|..||||.||:||||.||:..||.|||::::|:||:|||
Human   111 RVALKGNIET-NHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEY 174

  Fly   178 AMLEHESVPGIVESMKVVTVENAERVARYAFEFARQNNRKKVTTIHKANIMKLSDGLFLEVANRV 242
            :.||||||.|:|||:|::|...:.|:|.|||:.|:::.|||||.:||||||||.|||||:....|
Human   175 SSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREV 239

  Fly   243 HKDYPELEHNNMIIDNTCMQSVSNPHQFDVMNMTNLYGTIVSNVLCGLMGGAGLISGRNYGDHYA 307
            ...||::...|||:|||.||.||.|.|||||.|.||||.||:||..||:||.||::|.|||..||
Human   240 AARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYA 304

  Fly   308 IFEPGTRNTGTAIAGKNIANPVAMISASIDMLNHLGHKEHANVIQEAVYQTIVNDAIRTPDIGGT 372
            :||..|||||.:||.||||||.|.:.||..||:||....:|..|::||..::.|:.:.||||||.
Human   305 VFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQ 369

  Fly   373 NSSTDVVENILK 384
            .::::.::::::
Human   370 GTTSEAIQDVIR 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3g	NP_651416.1	mito_nad_idh	55..386	CDD:272942	176/332 (53%)
IDH3G	NP_004126.1	mito_nad_idh	52..383	CDD:272942	176/332 (53%)