DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5028 and Idh3g

DIOPT Version :9

Sequence 1:	NP_001097922.1	Gene:	CG5028 / 43102	FlyBaseID:	FBgn0039358	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	XP_006229613.1	Gene:	Idh3g / 25179	RGDID:	2863	Length:	395	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	194/392 - (49%)
Similarity:	267/392 - (68%)	Gaps:	10/392 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RLLQTQT-PFLTRGYPLLVTKEKTEDVAH--TKSALQKKVTGTDIPSAQYGGRHAVTMLPGGGIG 69
            |.|.|.| |:|..|..|:..:|.|:...|  ....|.........|||:|||||.|||:||.|||
  Rat     4 RSLGTATLPWLACGLVLVGRRELTQARVHIGVSKGLPSPFPFFQPPSAKYGGRHTVTMIPGDGIG 68

  Fly    70 PELMGYVREIFRYCGAPIDFEVIDIDPSTEGNDDLDYAITSIKRNGVALKGNIETKSQSL--TEV 132
            ||||.:|:.:||:...|:|||.:.:. |....:|:..||.:|:||.||||||||| :.:|  :..
  Rat    69 PELMLHVKSVFRHACVPVDFEEVHVS-SNADEEDIRNAIMAIRRNRVALKGNIET-NHNLPPSHK 131

  Fly   133 SRNVAIRNELDLYVNVVHCKSYPGIPARHHDIDVVLIRQNTDGEYAMLEHESVPGIVESMKVVTV 197
            |||..:|..||||.||:||||.||:..||.|||::::|:||:|||:.||||||.|:|||:|::|.
  Rat   132 SRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITK 196

  Fly   198 ENAERVARYAFEFARQNNRKKVTTIHKANIMKLSDGLFLEVANRVHKDYPELEHNNMIIDNTCMQ 262
            ..:.|:|.|||:.|:::.|||||.:||||||||.|||||:....|...||::..::||:|||.||
  Rat   197 AKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFDSMIVDNTTMQ 261

  Fly   263 SVSNPHQFDVMNMTNLYGTIVSNVLCGLMGGAGLISGRNYGDHYAIFEPGTRNTGTAIAGKNIAN 327
            .||.|.|||||.|.||||.||:||..||:||.||::|.|||..||:||..|||||.:||.|||||
  Rat   262 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIAN 326

  Fly   328 PVAMISASIDMLNHLGHKEHANVIQEAVYQTIVNDAIRTPDIGGTNSSTDVVENI---LKILSAK 389
            |.|.:.||..||:||....:|..|::||..::.|:.:.||||||..:::..:::|   ::|::.:
  Rat   327 PTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHIRIINGR 391

  Fly   390 RV 391
            .|
  Rat   392 AV 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5028	NP_001097922.1	mito_nad_idh	55..386	CDD:272942	176/335 (53%)
Idh3g	XP_006229613.1	mito_nad_idh	54..385	CDD:272942	176/332 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353519
Domainoid	1	1.000	345	1.000	Domainoid score	I1019
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55803
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2070
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	1	1.000	-	-		otm45435
orthoMCL	1	0.900	-	-		OOG6_101342
Panther	1	1.100	-	-	LDO	PTHR11835
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910