DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4743 and aralar1

DIOPT Version :9

Sequence 1:	NP_651415.1	Gene:	CG4743 / 43101	FlyBaseID:	FBgn0039357	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	88/314 - (28%)
Similarity:	130/314 - (41%)	Gaps:	63/314 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 MQEPVNKLKFFHAL------VAGGVAGMVVDIALFPIDTVKTRLQSELGFWRAG----------- 65
            ::.|.::..|...|      ..|..||.|....::|||.||||:|::    |||
  Fly   339 VESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQ----RAGSYIGEVAYRNS 399

  Fly    66 -----------GFRGIYKGLAPAAAGSAPTAALFFCTYECGKQFLSSVTQTKDS--PYVHMAAAS 117
                       ||.|:|:||.|...|.||..|:.....:..:   ..:|..|.:  .:..:.|..
  Fly   400 WDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVR---DKLTDKKGNIPTWAEVLAGG 461

  Fly   118 AAEVLACLIRVPVEIAKQRSQTLQGNKQSGLQILLRAY---RTEGLKRGLYRGFGSTIMREIPFS 179
            .|.....:...|:||.|.|.| :.|...||.:|  ||:   |..|| .|||:|..:.::|::|||
  Fly   462 CAGASQVVFTNPLEIVKIRLQ-VAGEIASGSKI--RAWSVVRELGL-FGLYKGARACLLRDVPFS 522

  Fly   180 LIQFPLWEYFKLQWTPLTGFDSTPFSVALCGAVAGGISAGLTTPLDVVKTRIMLAERESLNRRRS 244
            .|.||.:.:.|.......|::. |.::...||:||..:|.|.||.||:|||:.:..|........
  Fly   523 AIYFPTYAHTKAMMADKDGYNH-PLTLLAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTTYTG 586

  Fly   245 ARRILHGIYLERGFSGLFAGFVPRVLWITLGGAFF-----FGF----YDLTTRI 289
            .......|..|.|         ||..|.......|     ||.    |:|..|:
  Fly   587 VWDATKKIMAEEG---------PRAFWKGTAARVFRSSPQFGVTLVTYELLQRL 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4743	NP_651415.1	Mito_carr	23..99	CDD:278578	28/103 (27%)
		PTZ00168	25..281	CDD:185494	82/293 (28%)
		Mito_carr	199..291	CDD:278578	27/100 (27%)
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	28/104 (27%)
		PTZ00169	358..631	CDD:240302	84/293 (29%)
		Mito_carr	449..539	CDD:278578	29/93 (31%)
		Mito_carr	544..633	CDD:278578	27/98 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441977
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840