DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4730 and Zfp1

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_017456932.1	Gene:	Zfp1 / 498952	RGDID:	1565049	Length:	487	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	98/389 - (25%)
Similarity:	153/389 - (39%)	Gaps:	94/389 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LVSHEVSLSDSTTSLELSNCCRLCLEEPYPNQ-MLDMTVIYDQEAALSYYDCYEI--CTKEDLRQ 88
            |.|..||.:|.|.......     .|:..|:| :|.|.|:.:..:.|...:.::.  ..::|.|:
  Rat    87 LASGSVSFTDVTVDFSQEE-----WEQLDPSQRILYMDVMLENYSNLLSVEVWKADDQVEKDPRE 146

  Fly    89 ---------NPKNEPRT------LCKRCAV--------ELKWAYDFHKKMAIANQQLREIFVATE 130
                     .|||:|.|      ..||..:        ::.:.|..:.|..:.|..|.
  Rat   147 PDKQAPSLTTPKNQPPTEERGSLFGKRLNLNTDLVSLRQVPYKYYLYGKTLMYNSDLL------- 204

  Fly   131 ANTEQEDDVEDEENEADMNEEFLMEEIEEKQETP---------------------------IDSL 168
              :.:...||..:....:.|..|.    .|||.|                           |.||
  Rat   205 --SSRSCVVEKGDECGGLGEPLLY----LKQEKPHAGLQYSEYNGNGRSLSHTDAIFKHQKIKSL 263

  Fly   169 ED----------------IVPRNR-HTGKS--NCKFCHKEFRNHSRMAKHQMIHLANRPNFRCSQ 214
            ..                :|...| |||:.  .|..|.|.|.:.:.:.|||.||...:| |.|.:
  Rat   264 VQPFVCNYCDKAFSFKSLLVSHKRIHTGEKPYECNVCQKTFSHKANLIKHQRIHTGEKP-FECPE 327

  Fly   215 CDRVYLTKQALKVHVDSKHRQSGVHCDTCGKVFAIAKALEIHKRYHNRDFPYSCDLCDRRFAQRS 279
            |.:.:..:..|.||..:...:....|:.|||.||....|..|:|.|..:.||.|:.|.:.|.::|
  Rat   328 CGKAFTHQSNLIVHQRAHMAKKPYGCNECGKTFAQKFELTTHQRIHTGERPYECNECAKTFFKKS 392

  Fly   280 HLTVHQQVKHSGSRFICEFPGCQKSFTSSSSLRNHECTHTA-MPFECAHCHQSYPARNKLRMHL 342
            :|.:||::.....|:.|.  .|.|||..:|.|..|..|||. .|:||..|.:::..|:.||:||
  Rat   393 NLIIHQKIHTGEKRYECS--ECGKSFIQNSQLIIHRRTHTGEKPYECTECGKTFSQRSTLRLHL 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071	20/103 (19%)
		C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..232	CDD:275368	5/19 (26%)
		C2H2 Zn finger	240..260	CDD:275368	9/19 (47%)
		C2H2 Zn finger	268..289	CDD:275368	7/20 (35%)
		C2H2 Zn finger	296..318	CDD:275368	8/21 (38%)
		C2H2 Zn finger	325..346	CDD:275368	7/18 (39%)
Zfp1	XP_017456932.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910