DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4730 and sqz

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	67/302 - (22%)
Similarity:	113/302 - (37%)	Gaps:	57/302 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 DLRQNPKNEPRTLCKRCAVELKWAYDFHKKMAIANQQLR-------------------EIFVATE 130
            :.|||       :.:|....||.....|::..:..||..                   ::.|:..
  Fly    46 EFRQN-------VAERLDYSLKNGLVQHQQQMVMEQQPHPDQQQQQHLHHPQQQQHPPQLKVSYS 103

  Fly   131 ANTEQEDDVEDEENEADMNEEFLMEEIEEKQETPIDSLEDIVPRNRHTGKS----NCKFCHKEFR 191
            |........|.:|.:.|.|.....:::.....:..:.........|..|..    .|..|.|.|.
  Fly   104 APNSPPTPHEQQEQKYDPNRSPPRQQMSSASGSGSNGSSPEEESRRGDGDQAKPYKCGSCSKSFA 168

  Fly   192 NHSRMAKHQMIHLANRPNFRCSQCDRVYLTKQALKVHVDS-------KHRQSGVHCDTCGKVFAI 249
            |.|.:::|..|||..:| :||..|.|.:.....|:.|:.:       |.|.:|     |.|.|:.
  Fly   169 NSSYLSQHTRIHLGIKP-YRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAG-----CPKAFSQ 227

  Fly   250 AKALEIHKRYHNRDFPYSCDLCDRRFAQR----SHLTVHQQVKHSGSRFICEFPGCQKSFTSSSS 310
            ...|:.|.|.|..|.|:.|:.|.:.|:..    .|:..|:..||..:. ||..  |.||:|..:.
  Fly   228 LSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHLKTH-ICNL--CGKSYTQETY 289

  Fly   311 LRNHECTHTAMPFECAH-------CHQSYPARNKLRMHLERK 345
            |:.|...|.....:..|       .||.:...:.:.::|:|:
  Fly   290 LQKHLQKHAEKAEKQQHRHTAQVAAHQQHVPASGIGLNLQRQ 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071	9/57 (16%)
		C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..232	CDD:275368	5/26 (19%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		C2H2 Zn finger	268..289	CDD:275368	5/24 (21%)
		C2H2 Zn finger	296..318	CDD:275368	7/21 (33%)
		C2H2 Zn finger	325..346	CDD:275368	5/28 (18%)
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	7/19 (37%)
		zf-H2C2_2	172..197	CDD:290200	9/25 (36%)
		zf-C2H2	186..208	CDD:278523	6/21 (29%)
		C2H2 Zn finger	188..208	CDD:275368	5/19 (26%)
		zf-C2H2_8	191..271	CDD:292531	21/84 (25%)
		zf-H2C2_2	200..227	CDD:290200	8/31 (26%)
		C2H2 Zn finger	216..238	CDD:275368	8/26 (31%)
		C2H2 Zn finger	246..266	CDD:275368	4/19 (21%)
		C2H2 Zn finger	277..297	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457137
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3043
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.880