DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4730 and CG1603

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001260778.1	Gene:	CG1603 / 35683	FlyBaseID:	FBgn0033185	Length:	586	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	75/329 - (22%)
Similarity:	126/329 - (38%)	Gaps:	68/329 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 APVKLVSHEVSLSDSTTSLELS----NCCRLCLEEPYPNQMLDMTVIYDQEAALSYYDCYEICTK 83
            ||| :...|....:..|:::|:    |.......|.|.|    ..|:|:|  ||..:...||...
  Fly   290 APV-VTPRENEEDNDLTAIKLNFKEENLITTSFIETYAN----YPVLYNQ--ALPDFGSIEIRAD 347

  Fly    84 EDLRQNPKNEPRTLCKRCAVEL------KWAYDFHKKM-------AIANQQLREI----FVATEA 131
            ...|...:.:|........|.:      :|.||..:::       ..:.|:::.:    |:..:.
  Fly   348 AFKRMAKEFQPVVKANETDVYIAVNKLRRWLYDAIRRLKSKELIQKCSKQEVQYLQMCSFLPAKG 412

  Fly   132 NTEQ--EDDVEDEENEADMNEEFLMEEIEEKQETPIDSLEDIVPRNRHTGKSNCKFCHKEFRNHS 194
            :..|  ..|..|:....|.|....:.:..|..:.|.                .|.||.:.|..|.
  Fly   413 SESQVLYCDYCDKRFHGDYNLRVHIVKAHEVGDLPY----------------LCSFCPRRFDRHV 461

  Fly   195 RMAKHQMIHLANRPNF----RCSQCDRVYLTKQALKVHVDSKHRQSGVH-CDTCGKVFAIAKALE 254
            .|.:|::     |.:|    :|..|::.:.....||||. ..|.....| ||.|||.|.:...|:
  Fly   462 DMDRHKL-----RSHFERKLKCQYCEKSFAVDTDLKVHT-LIHTGERPHVCDICGKTFRLKLLLD 520

  Fly   255 IH-KRYHNRDFPYSCDLCDRRFAQR----SHLTVHQQVKHSGSRFICEFPGCQKSFTSSSSLRNH 314
            .| ...|....||||::|.:.|.::    :|:..|..::...    ||:  |..:|...|||..|
  Fly   521 HHVNGVHLNIRPYSCNMCTKTFRKKFELANHIKGHLNIRDKK----CEY--CDATFYDHSSLSRH 579

  Fly   315 ECTH 318
            ..:|
  Fly   580 RRSH 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071	17/90 (19%)
		C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		C2H2 Zn finger	240..260	CDD:275368	8/20 (40%)
		C2H2 Zn finger	268..289	CDD:275368	5/24 (21%)
		C2H2 Zn finger	296..318	CDD:275368	8/21 (38%)
		C2H2 Zn finger	325..346	CDD:275368
CG1603	NP_001260778.1	MADF_DNA_bdg	202..287	CDD:287510
		GT1	321..408	CDD:304916	17/92 (18%)
		C2H2 Zn finger	420..441	CDD:275368	4/20 (20%)
		COG5048	<424..583	CDD:227381	47/186 (25%)
		C2H2 Zn finger	450..471	CDD:275368	8/25 (32%)
		C2H2 Zn finger	478..498	CDD:275368	6/20 (30%)
		zf-H2C2_2	490..513	CDD:290200	11/23 (48%)
		C2H2 Zn finger	506..527	CDD:275368	8/20 (40%)
		C2H2 Zn finger	535..555	CDD:275368	4/19 (21%)
		C2H2 Zn finger	563..583	CDD:275368	8/21 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457185
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930