DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4730 and wor

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	80/323 - (24%)
Similarity:	124/323 - (38%)	Gaps:	77/323 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LEEPYPNQMLDMTVIYDQEAALSYYDCYEICTKEDLRQNPKNEPRTLCKRCAV--------ELKW 107
            :||...||  |:..:..:.:...||.|.:                  |.:|..        :...
  Fly   246 MEEDQENQ--DINQLKIKSSNDLYYQCQQ------------------CNKCYATYAGLVKHQQTH 290

  Fly   108 AYDFHKKMAIANQQ--LREIFVATEANTEQEDDVEDEENEADMNEEFLMEEIEEKQETPIDSLED 170
            ||:..:...|.:|.  ...|...||..|:|...:....|.|.          .:..:.|:.
  Fly   291 AYESTEYKIIRSQPGGSGAIVDQTEFCTDQASALIQAANVAS----------AQSMQKPVG---- 341

  Fly   171 IVPRNRHTGKSNCKFCHKEFRNHSRMAKHQMIHLAN------RPNFRCSQCDRVYLTKQALKVHV 229
             |||      .:|:.|.|.:..:|.::|||..|..:      :..|.|..||:.|::..|||:|:
  Fly   342 -VPR------YHCQDCGKSYSTYSGLSKHQQFHCPSAEGNQVKKVFSCKNCDKTYVSLGALKMHI 399

  Fly   230 DSKHRQSGVHCDTCGKVFAIAKALEIHKRYHNRDFPYSCDLCDRRFAQRSHLTVHQQVKHSGSRF 294
              :.......|..|||.|:....|:.|.|.|..:.|:||..|:|.||.||:|..|.|......::
  Fly   400 --RTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKY 462

  Fly   295 ICEFPGCQKSFTSSSSLRNHECTHTAMPFECAHCHQSYPA-------RNKLRMHL---ERKHN 347
            .|  |.|.|||:..|.|..|      :...|.......|:       :.:|:.||   |..||
  Fly   463 SC--PTCTKSFSRMSLLAKH------LQSGCQTEQSGGPSGSGGGFDQQQLQQHLQVYEEGHN 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071	14/82 (17%)
		C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..232	CDD:275368	8/19 (42%)
		C2H2 Zn finger	240..260	CDD:275368	8/19 (42%)
		C2H2 Zn finger	268..289	CDD:275368	10/20 (50%)
		C2H2 Zn finger	296..318	CDD:275368	9/21 (43%)
		C2H2 Zn finger	325..346	CDD:275368	6/30 (20%)
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	3/37 (8%)
		C2H2 Zn finger	317..334	CDD:275368	4/26 (15%)
		zf-C2H2	345..367	CDD:278523	7/21 (33%)
		C2H2 Zn finger	347..367	CDD:275368	7/19 (37%)
		PHA00732	379..>417	CDD:177300	14/39 (36%)
		C2H2 Zn finger	382..402	CDD:275368	8/21 (38%)
		zf-C2H2_8	405..482	CDD:292531	30/84 (36%)
		zf-C2H2	406..428	CDD:278523	8/21 (38%)
		C2H2 Zn finger	408..428	CDD:275368	8/19 (42%)
		zf-H2C2_2	421..444	CDD:290200	9/22 (41%)
		zf-C2H2	434..456	CDD:278523	11/21 (52%)
		C2H2 Zn finger	436..456	CDD:275368	10/19 (53%)
		zf-H2C2_2	448..473	CDD:290200	9/26 (35%)
		C2H2 Zn finger	464..481	CDD:275368	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457217
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930