DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4730 and Kr-h1

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_477466.1	Gene:	Kr-h1 / 33861	FlyBaseID:	FBgn0266450	Length:	845	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	73/275 - (26%)
Similarity:	116/275 - (42%)	Gaps:	46/275 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LRQNPKNEPRTLCKRCAVEL--KWAYDFHKKMAIANQQL-----REIFVATEANTEQEDDVEDEE 143
            :|:...::|:..|.:|.:..  |.|:..|.|....||.|     ....||...:|     ...|.
  Fly   184 VRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVST-----AAIEL 243

  Fly   144 NEADMNEEFLMEEIEEKQETPIDSLEDIVPR--------NRHTGKS--NCKFCHKEFRNHSRMAK 198
            |:|.:               |:.     :|:        |...|..  .|..|.|.|...:|:.:
  Fly   244 NDAGL---------------PVG-----IPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIR 288

  Fly   199 HQMIHLANRPNFRCSQCDRVYLTKQALKVHVDSKHRQSGVHCDTCGKVFAIAKALEIHKRYHNRD 263
            |...|...|| |.|..|.:::..|:.|:||.....::....||.||:.|..:..|..|.|.|..:
  Fly   289 HYRTHTGERP-FECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGE 352

  Fly   264 FPYSCDLCDRRFAQRSHLTVHQQVKHSGSR-FICEFPGCQKSFTSSSSLRNHECTHTA-MPFECA 326
            .|:.|.:|::.|.|...|.:|.:. |:|.: :.|..|||.|.||.|..|:.|..|||. .|:.|.
  Fly   353 RPHKCSVCEKTFIQSGQLVIHMRT-HTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCD 416

  Fly   327 HCHQSYPARNKLRMH 341
            .|.:.:...:.|::|
  Fly   417 ICFRDFGYNHVLKLH 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071	11/44 (25%)
		C2H2 Zn finger	183..203	CDD:275368	6/19 (32%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		C2H2 Zn finger	240..260	CDD:275368	8/19 (42%)
		C2H2 Zn finger	268..289	CDD:275368	6/20 (30%)
		C2H2 Zn finger	296..318	CDD:275368	10/21 (48%)
		C2H2 Zn finger	325..346	CDD:275368	4/17 (24%)
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		COG5048	<270..420	CDD:227381	50/151 (33%)
		zf-C2H2	271..293	CDD:278523	6/21 (29%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..309	CDD:290200	7/23 (30%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)
		zf-H2C2_2	313..338	CDD:290200	8/24 (33%)
		C2H2 Zn finger	329..349	CDD:275368	8/19 (42%)
		zf-H2C2_2	344..366	CDD:290200	7/21 (33%)
		C2H2 Zn finger	357..377	CDD:275368	6/20 (30%)
		zf-H2C2_2	370..396	CDD:290200	10/26 (38%)
		C2H2 Zn finger	385..407	CDD:275368	10/21 (48%)
		zf-H2C2_2	400..424	CDD:290200	8/23 (35%)
		C2H2 Zn finger	415..435	CDD:275368	4/17 (24%)
		zf-C2H2	441..463	CDD:278523
		C2H2 Zn finger	443..463	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100