DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4730 and zld

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001285466.1	Gene:	zld / 32994	FlyBaseID:	FBgn0259789	Length:	1596	Species:	Drosophila melanogaster

Alignment Length:	326	Identity:	59/326 - (18%)
Similarity:	113/326 - (34%)	Gaps:	119/326 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RRTAEAPVKLV-----SHEVSLSDSTTSLELSNCCRLCLEEPYPNQMLDMTVIYDQEAALSYYDC 77
            ::.|:.|...|     |..||.|.:|.:||:                       |....:.::..
  Fly  1204 QQEAQTPTLTVLSTPYSPTVSSSRATPALEM-----------------------DMATLMQHHQD 1245

  Fly    78 YEICTKEDLRQNPKNEPRTLCKRCAVELKWAYDFHKKMAIANQQLREIFVATEANTEQEDDVEDE 142
            ||:                                ::..:.:|||.::    :.:.:|.|..:.:
  Fly  1246 YEM--------------------------------EQYQMQHQQLDQM----QQHQQQLDHQQQQ 1274

  Fly   143 ENEADMNEEFLMEEIEEKQE----TPIDSLEDIVPRNRH--------------TGKSNCKFCHKE 189
            :..||..:....:.:.:|:.    ||     ....|.|:              :|:..|..|.||
  Fly  1275 QILADQTQTMAQQPLAKKRRGGNATP-----STTKRRRNSSVGSTSPHSTTLPSGRIKCLECDKE 1334

  Fly   190 FRNHSRMAKH-QMIHLANRPNFRCSQCDRVYLTKQALKVHVDSKHRQSGVHCDTCGKVFAIAKAL 253
            |..:..:.:| :..|....| |||.:|.:.:.::.....|:.
  Fly  1335 FTKNCYLTQHNKSFHSGEYP-FRCQKCGKRFQSEDVYTTHLG----------------------- 1375

  Fly   254 EIHKRYHNRDFPYSCDLCDRRFAQRSHLTVHQQVKHSG-SRFICEFPGCQKSFTSSSSLRNHECT 317
                |:..:|.|:.|:||.::|..::.|..|.:..|:| .:.:|:.  |:|.|.....||.|..|
  Fly  1376 ----RHRTQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDI--CEKGFCRKDHLRKHLET 1434

  Fly   318 H 318
            |
  Fly  1435 H 1435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071	6/77 (8%)
		C2H2 Zn finger	183..203	CDD:275368	6/20 (30%)
		C2H2 Zn finger	212..232	CDD:275368	3/19 (16%)
		C2H2 Zn finger	240..260	CDD:275368	1/19 (5%)
		C2H2 Zn finger	268..289	CDD:275368	6/20 (30%)
		C2H2 Zn finger	296..318	CDD:275368	7/21 (33%)
		C2H2 Zn finger	325..346	CDD:275368
zld	NP_001285466.1	zf-C2H2_jaz	552..577	CDD:288983
		LIM	1328..1389	CDD:259829	17/88 (19%)
		C2H2 Zn finger	1328..1349	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1357..1377	CDD:275368	3/46 (7%)
		C2H2 Zn finger	1386..1407	CDD:275368	6/20 (30%)
		zf-H2C2_2	1398..1422	CDD:290200	7/25 (28%)
		zf-C2H2	1413..1435	CDD:278523	7/23 (30%)
		C2H2 Zn finger	1415..1435	CDD:275368	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930