DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4730 and CG42726

DIOPT Version :9

Sequence 1:	NP_001262965.1	Gene:	CG4730 / 43099	FlyBaseID:	FBgn0039355	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	202	Identity:	57/202 - (28%)
Similarity:	92/202 - (45%)	Gaps:	21/202 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 EIEEKQETPIDSLED----IVPRNRHTGKSNCKFCHKEFRNHSRMAKHQMIHLANRPNFRCSQCD 216
            :|:|.|||...:..|    :..:..|     |..|:|:||:.::...|..........|.|.:|.
  Fly    48 DIQETQETQARTSADKRIIVTDKGYH-----CTVCNKDFRSRTQQYYHLTCGNDLLKKFNCKECG 107

  Fly   217 RVYLTKQALKVHVDSKHRQSGVHCDTCGKVFAIAKALEIHKRYHNRDFPYSCDLCDRRFAQR--- 278
            |.:.|...||.|:.|..:||...|..|.|.|.....|:.|...||:: .:.|.:|.:.|.::
  Fly   108 RRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQE-KHLCPICQKVFRRKSSL 171

  Fly   279 -SHLTVHQQVKHSGSRFICEFPGCQKSFTSSSSLRNHECTH--TAMPFECAHCHQSYPARNKLRM 340
             |||.:|..:   |.:|.||.  |.|.|.:.::|..|...|  ..:...|..|.:|:..:..||:
  Fly   172 ASHLAIHSDL---GLQFKCEL--CSKHFQNKANLNQHLRKHDKNNIRHMCKVCQKSFLRQTTLRL 231

  Fly   341 HLERKHN 347
            |::|..|
  Fly   232 HMKRHSN 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_001262965.1	zf-AD	46..124	CDD:285071
		C2H2 Zn finger	183..203	CDD:275368	6/19 (32%)
		C2H2 Zn finger	212..232	CDD:275368	7/19 (37%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		C2H2 Zn finger	268..289	CDD:275368	7/24 (29%)
		C2H2 Zn finger	296..318	CDD:275368	7/21 (33%)
		C2H2 Zn finger	325..346	CDD:275368	7/20 (35%)
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368	6/19 (32%)
		C2H2 Zn finger	103..123	CDD:275368	7/19 (37%)
		COG5048	<112..288	CDD:227381	40/133 (30%)
		C2H2 Zn finger	131..151	CDD:275368	6/19 (32%)
		Chordopox_A33R	151..>254	CDD:283591	27/94 (29%)
		C2H2 Zn finger	158..178	CDD:275368	6/19 (32%)
		C2H2 Zn finger	187..207	CDD:275368	7/21 (33%)
		C2H2 Zn finger	216..236	CDD:275368	6/19 (32%)
		C2H2 Zn finger	244..264	CDD:275368
		C2H2 Zn finger	272..290	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468434
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930