Protein Alignment CG4730 and ZNF660

DIOPT Version :10

• Sequence 1: NP_651413.1
• Gene: CG4730 / 43099
• FlyBaseID: FBgn0039355
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_775929.2
• Gene: ZNF660 / 285349
• HGNCID: 26720
• Length: 331
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 87/356 - (24%)
• Similarity: 147/356 - (41%)
• Gaps: 59/356 - (16%)

  Fly    18 RRTAEAPVKLVSHEVSL---SDSTTSLELSNCCRLCLEEPYPNQMLDMTVIYDQEAALSYYDCYE 79
            |:|.....|.|.....|   ||..:..:.|.||     :|..|:.:        :|....|.|.|
Human     3 RKTRNFKHKTVKDNKVLTEGSDQESEKDNSQCC-----DPATNERV--------QAEKRQYVCTE 54

  Fly    80 ICTK-----EDLRQNPK---NEPRTLCKRCAVELKWAYDFHKKMAIANQQLREIFVATEANTEQE 136
             |.|     .:|..:.:   .|....||.|.....     |....:.::::         :|..:
Human    55 -CGKAFSQSANLTVHERIHTGEKPYKCKECGKAFS-----HSSNLVVHRRI---------HTGLK 104

  Fly   137 DDVEDEENEADMNEEFLM--------EEIEEKQE--TPIDSLEDIVPRNR-HTGKS--NCKFCHK 188
            .....|..::...:..|:        |:..|.:|  ........::..:| |||:.  :|..|.|
Human   105 PYTCSECGKSFSGKSHLIRHQGIHSGEKTYECKECGKAFSRSSGLISHHRVHTGEKPYSCIECGK 169

  Fly   189 EFRNHSRMAKHQMIHLANRPNFRCSQCDRVYLTKQALKVHVDSKHRQSGVHCDTCGKVFAIAKAL 253
            .|...|.:.:||.:|...:. ::|.:|.:...:...:..|......:....||.|||.|.:.|.|
Human   170 AFSRSSNLTQHQRMHRGKKV-YKCKECGKTCGSNTKIMDHQRIHTGEKPYECDECGKTFILRKTL 233

  Fly   254 EIHKRYHNRDFPYSCDLCDRRFAQRSHLTVHQQVKHSGSR-FICEFPGCQKSFTSSSSLRNHECT 317
            ..|:|.|.|:.||.|:.|.:.|....:|..||:| |:|.: :.|.  .|.|:|..:|.:..|..|
Human   234 NEHQRLHRREKPYKCNECGKAFTSNRNLVDHQRV-HTGEKPYKCN--ECGKTFRQTSQVILHLRT 295

  Fly   318 HT-AMPFECAHCHQSYPARNKLRMHLERKHN 347
            || ..|::|:.|.::|...::|..| :||||
Human   296 HTKEKPYKCSECGKAYRYSSQLIQH-QRKHN 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4730	NP_651413.1	zf-AD	46..124	CDD:462262	16/85 (19%)
		C2H2 Zn finger	183..203	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..232	CDD:275368	3/19 (16%)
		C2H2 Zn finger	240..260	CDD:275368	10/19 (53%)
		C2H2 Zn finger	268..289	CDD:275368	7/20 (35%)
		C2H2 Zn finger	296..318	CDD:275368	6/21 (29%)
		C2H2 Zn finger	325..346	CDD:275368	6/20 (30%)
ZNF660	NP_775929.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		8/31 (26%)
		C2H2 Zn finger	52..72	CDD:275368	5/20 (25%)
		zf-H2C2_2	64..89	CDD:463886	5/29 (17%)
		C2H2 Zn finger	80..100	CDD:275368	4/33 (12%)
		COG5048	<107..294	CDD:227381	49/190 (26%)
		C2H2 Zn finger	108..128	CDD:275368	2/19 (11%)
		C2H2 Zn finger	136..156	CDD:275368	2/19 (11%)
		C2H2 Zn finger	164..184	CDD:275368	7/19 (37%)
		C2H2 Zn finger	192..207	CDD:275368	2/14 (14%)
		C2H2 Zn finger	220..240	CDD:275368	10/19 (53%)
		C2H2 Zn finger	248..268	CDD:275368	7/20 (35%)
		C2H2 Zn finger	276..296	CDD:275368	6/21 (29%)
		C2H2 Zn finger	304..324	CDD:275368	6/20 (30%)