| Sequence 1: | NP_733115.1 | Gene: | Lgr3 / 43098 | FlyBaseID: | FBgn0039354 | Length: | 765 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001017403.1 | Gene: | LGR6 / 59352 | HGNCID: | 19719 | Length: | 967 | Species: | Homo sapiens |
| Alignment Length: | 765 | Identity: | 174/765 - (22%) |
|---|---|---|---|
| Similarity: | 278/765 - (36%) | Gaps: | 214/765 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 153 RLSSEVTNLIIIRN--------NLTLRDNIFA--------NFTRLQKLTLKYNNISRVPLGSFSG 201
Fly 202 LFHLERLELSHNNVSHLPHGVFLGLHSLQWLFLVNNHLHHLPV--------EQLRFFRR------ 252
Fly 253 --------------------------------------------------------LEWLVLSR- 260
Fly 261 ----------------NRLTLRNVQLPKIPTLY------EVYLDFNRIEYIGEETFSQLDNLHLL 303
Fly 304 DLQHNLITHIHGRAFANLTNMRDIRLVGN-----PIKELSGETFLHNTRLE---ALSLALMPIHI 360
Fly 361 SSSLMEPLNI----------------SFLNLTGIRYD----HIDFEAINSMRNLTYII------Y 399
Fly 400 DR---FFYCSMT-----PRVRMCKPSTDGVSSFQDLLSKPVLRYSAWVMATLTIAGNVLVLWGRF 456
Fly 457 IYRDENV-AVTMVIRNLALADMLMGFYLVTIGVQDYRYRNEYYKVVLDWITSWQCTLIGTLAVSS 520
Fly 521 SEVSMLILAFMSLERFLLIA-------DPFRGHRSIGNRVMWLALICIWITGVGLAVAPVLLWRT 578
Fly 579 STLPYYGSYSGTCFPLHIHEAFPMGWLYSAFVFLGVNLLLLVMIAMLYTALLI--------SIWR 635
Fly 636 TRSATPLTLLDCEFAVRFFFIVLTDFLCWVPIIVMKIWVFFN-YNISDDIYAWLVVFVLPLNSAV 699
Fly 700 NPLLYTFTTPKYRNQIFLRGWKKITSRKRAEAG-NGNVATTTTGTATGSS 748 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lgr3 | NP_733115.1 | LDLa | 32..65 | CDD:238060 | |
| LRR_8 | 179..239 | CDD:290566 | 24/59 (41%) | ||
| leucine-rich repeat | 181..204 | CDD:275380 | 10/22 (45%) | ||
| LRR_RI | <196..354 | CDD:238064 | 64/258 (25%) | ||
| leucine-rich repeat | 205..228 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 229..252 | CDD:275380 | 9/30 (30%) | ||
| leucine-rich repeat | 253..275 | CDD:275380 | 8/38 (21%) | ||
| LRR_8 | 274..334 | CDD:290566 | 27/70 (39%) | ||
| leucine-rich repeat | 276..299 | CDD:275380 | 13/28 (46%) | ||
| leucine-rich repeat | 300..323 | CDD:275380 | 11/22 (50%) | ||
| leucine-rich repeat | 324..347 | CDD:275380 | 6/27 (22%) | ||
| 7tm_1 | 447..704 | CDD:278431 | 56/273 (21%) | ||
| LGR6 | NP_001017403.1 | LRRNT | 34..68 | CDD:214470 | |
| LRR_RI | <57..199 | CDD:238064 | 14/54 (26%) | ||
| leucine-rich repeat | 70..91 | CDD:275380 | |||
| LRR 1 | 91..112 | ||||
| LRR_8 | 92..150 | CDD:290566 | 2/5 (40%) | ||
| leucine-rich repeat | 92..115 | CDD:275380 | |||
| LRR 2 | 115..136 | ||||
| leucine-rich repeat | 116..139 | CDD:275380 | |||
| LRR_RI | 131..392 | CDD:238064 | 55/247 (22%) | ||
| LRR 3 | 139..160 | 4/15 (27%) | |||
| leucine-rich repeat | 140..163 | CDD:275380 | 4/18 (22%) | ||
| LRR 4 | 163..186 | 5/22 (23%) | |||
| leucine-rich repeat | 164..187 | CDD:275380 | 5/22 (23%) | ||
| LRR_8 | 186..246 | CDD:290566 | 24/59 (41%) | ||
| LRR 5 | 187..208 | 9/20 (45%) | |||
| leucine-rich repeat | 188..211 | CDD:275380 | 10/22 (45%) | ||
| LRR 6 | 211..232 | 7/20 (35%) | |||
| leucine-rich repeat | 212..235 | CDD:275380 | 9/22 (41%) | ||
| LRR 7 | 235..256 | 7/20 (35%) | |||
| leucine-rich repeat | 236..258 | CDD:275380 | 7/21 (33%) | ||
| LRR_8 | 258..314 | CDD:290566 | 2/55 (4%) | ||
| LRR 8 | 258..279 | 2/20 (10%) | |||
| leucine-rich repeat | 259..282 | CDD:275380 | 2/22 (9%) | ||
| LRR 9 | 282..303 | 0/20 (0%) | |||
| leucine-rich repeat | 283..304 | CDD:275380 | 0/20 (0%) | ||
| LRR 10 | 306..328 | 0/21 (0%) | |||
| LRR 11 | 329..350 | 5/20 (25%) | |||
| leucine-rich repeat | 330..344 | CDD:275378 | 5/13 (38%) | ||
| LRR 12 | 353..374 | 5/20 (25%) | |||
| leucine-rich repeat | 354..399 | CDD:275380 | 17/44 (39%) | ||
| LRR_8 | 375..434 | CDD:290566 | 25/58 (43%) | ||
| LRR 13 | 375..396 | 9/20 (45%) | |||
| leucine-rich repeat | 376..390 | CDD:275378 | 5/13 (38%) | ||
| LRR 14 | 399..420 | 10/20 (50%) | |||
| leucine-rich repeat | 400..423 | CDD:275380 | 11/22 (50%) | ||
| LRR 15 | 423..443 | 3/19 (16%) | |||
| leucine-rich repeat | 424..444 | CDD:275380 | 4/19 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2087 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||