DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lgr3 and lrrc57

DIOPT Version :9

Sequence 1:NP_733115.1 Gene:Lgr3 / 43098 FlyBaseID:FBgn0039354 Length:765 Species:Drosophila melanogaster
Sequence 2:NP_001002627.1 Gene:lrrc57 / 436900 ZFINID:ZDB-GENE-040718-372 Length:238 Species:Danio rerio


Alignment Length:242 Identity:66/242 - (27%)
Similarity:103/242 - (42%) Gaps:68/242 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 LQKLT-------LKYNNISRVP--LGSFSGLFHLERLELSHNNVSHLPHGVFLG-LHSLQWLFLV 235
            |||||       |..|.|..:|  :|||.   ||:...:|.|.::.||:.:  | |..|:.|.|.
Zfish    33 LQKLTANLRTVDLSNNKIEELPAFIGSFQ---HLKSFTISCNKLTSLPNDI--GKLKKLETLILN 92

  Fly   236 NNHLHHLP--VEQLRFFRRLEWLVLSRNRLTLRNVQLPKIPTLYEVYLDFNRIEYIGEETFSQLD 298
            .|.|..||  :.||:..|.|.   ||.|       |..:.|:              |..|..|||
Zfish    93 GNQLKQLPSSIGQLKSLRTLS---LSGN-------QFKEFPS--------------GLGTLRQLD 133

  Fly   299 NLHLLDLQHNLITHIHGRAFANLTNMRDIRL------VGNPIKELSGETFLHNTRLE--ALSLAL 355
               :|||..|.|..:.    |.:..::.|.:      :.:..:|:|....|...|||  .|.|:.
Zfish   134 ---VLDLSKNQIRVVP----AEVAELQAIEINLNQNQISSVTQEVSRTPRLKVLRLEENCLELSS 191

  Fly   356 MPIHISSSLMEPLNISFLNLTGIRYDHIDFEAINSMRNLTYIIYDRF 402
            :|:    |::....:|.|::.|..::      :..||:|..  ||::
Zfish   192 IPL----SILTDSQVSLLSVEGNLFE------VKKMRDLEG--YDKY 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lgr3NP_733115.1 LDLa 32..65 CDD:238060
LRR_8 179..239 CDD:290566 24/67 (36%)
leucine-rich repeat 181..204 CDD:275380 12/31 (39%)
LRR_RI <196..354 CDD:238064 46/168 (27%)
leucine-rich repeat 205..228 CDD:275380 7/23 (30%)
leucine-rich repeat 229..252 CDD:275380 9/24 (38%)
leucine-rich repeat 253..275 CDD:275380 5/21 (24%)
LRR_8 274..334 CDD:290566 13/65 (20%)
leucine-rich repeat 276..299 CDD:275380 4/22 (18%)
leucine-rich repeat 300..323 CDD:275380 6/22 (27%)
leucine-rich repeat 324..347 CDD:275380 4/28 (14%)
7tm_1 447..704 CDD:278431
lrrc57NP_001002627.1 LRR 1 10..36 2/2 (100%)
LRR_RI <37..191 CDD:238064 52/189 (28%)
LRR 2 37..62 8/27 (30%)
leucine-rich repeat 40..65 CDD:275380 9/27 (33%)
LRR_8 62..119 CDD:290566 22/68 (32%)
LRR 3 64..82 4/19 (21%)
leucine-rich repeat 66..85 CDD:275380 6/20 (30%)
LRR 4 83..106 8/22 (36%)
leucine-rich repeat 86..108 CDD:275380 9/21 (43%)
LRR 5 108..128 8/43 (19%)
leucine-rich repeat 109..131 CDD:275380 9/45 (20%)
LRR 6 129..152 9/29 (31%)
leucine-rich repeat 132..154 CDD:275380 8/28 (29%)
LRR 7 154..173 2/18 (11%)
leucine-rich repeat 155..176 CDD:275380 3/20 (15%)
LRR 8 174..199 8/28 (29%)
leucine-rich repeat 177..198 CDD:275380 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4149
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.030

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