| Sequence 1: | NP_733115.1 | Gene: | Lgr3 / 43098 | FlyBaseID: | FBgn0039354 | Length: | 765 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_775450.2 | Gene: | Lgr4 / 286994 | RGDID: | 628615 | Length: | 951 | Species: | Rattus norvegicus |
| Alignment Length: | 749 | Identity: | 173/749 - (23%) |
|---|---|---|---|
| Similarity: | 280/749 - (37%) | Gaps: | 203/749 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 109 SMVPRNQSLTLNMTCDIVTYPKACQCGQGTILYCGRYAKLRRFPRLSSEVTNLIIIRNN--LTLR 171
Fly 172 DNIFANFTRLQKLTLKYNNISRVPLGSFSGLFHLERLELSHNNVSHLPHGVFLG----------- 225
Fly 226 ----------------LHSL--------QW------------LFLVNNHLHHLPVEQLRFFRRLE 254
Fly 255 WLVLSRNRLTLRNVQLPKI---PTLYEVYLDFNRIEYIGEETFSQLDNLHLLDLQHNLITHIHGR 316
Fly 317 AFANL---TNMRDI---RLVGNPIKELSGETFLH---NTRL-EALSLALMPIHISSSLMEPLNIS 371
Fly 372 FLNLTGI----RYDHIDFEAINSMRNLT----------------------------------YII 398
Fly 399 YDRFFYCSMTPRVRMCKPSTDGVSSFQDLLSKPVLRYSAWVMATLTIAGNVLVLWGRFIYRDENV 463
Fly 464 AVTMVIRNLALADMLMGFYLVTIGVQDYRYRNEYYKVVLDWITSWQCTLIGTLAVSSSEVSMLIL 528
Fly 529 AFMSLERFLLIADPFRGHRSIGNRVMWLALICIWITGVGLAVAPVLLWRTSTLPYY--GSYSGT- 590
Fly 591 -CFPLHIHEAFPMGWLYSAFVFLGVNLLLLVMIAMLYTALLISIWR-----------TRSATPLT 643
Fly 644 LLDCEFAVRFFFIVLTDFLCWVPIIVMKIWVFFNYNISDDIYAWLVVFVLPLNSAVNPLLYTFTT 708
Fly 709 PKYRNQIFLRGWKKITSRKRAEAGNGNVATTTTG 742 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lgr3 | NP_733115.1 | LDLa | 32..65 | CDD:238060 | |
| LRR_8 | 179..239 | CDD:290566 | 24/106 (23%) | ||
| leucine-rich repeat | 181..204 | CDD:275380 | 8/22 (36%) | ||
| LRR_RI | <196..354 | CDD:238064 | 60/217 (28%) | ||
| leucine-rich repeat | 205..228 | CDD:275380 | 9/49 (18%) | ||
| leucine-rich repeat | 229..252 | CDD:275380 | 6/42 (14%) | ||
| leucine-rich repeat | 253..275 | CDD:275380 | 7/24 (29%) | ||
| LRR_8 | 274..334 | CDD:290566 | 27/65 (42%) | ||
| leucine-rich repeat | 276..299 | CDD:275380 | 10/22 (45%) | ||
| leucine-rich repeat | 300..323 | CDD:275380 | 13/25 (52%) | ||
| leucine-rich repeat | 324..347 | CDD:275380 | 7/28 (25%) | ||
| 7tm_1 | 447..704 | CDD:278431 | 60/271 (22%) | ||
| Lgr4 | NP_775450.2 | LRRNT | 29..61 | CDD:214470 | |
| LRR 1 | 58..79 | ||||
| leucine-rich repeat | 59..82 | CDD:275380 | |||
| LRR | <62..301 | CDD:227223 | 35/148 (24%) | ||
| LRR 2 | 82..103 | ||||
| leucine-rich repeat | 83..106 | CDD:275380 | |||
| LRR 3 | 106..127 | ||||
| leucine-rich repeat | 107..130 | CDD:275380 | |||
| LRR 4 | 130..151 | ||||
| leucine-rich repeat | 131..154 | CDD:275380 | |||
| LRR 5 | 154..177 | 1/2 (50%) | |||
| leucine-rich repeat | 155..178 | CDD:275380 | 1/3 (33%) | ||
| LRR 6 | 178..199 | 7/39 (18%) | |||
| leucine-rich repeat | 179..202 | CDD:275380 | 8/41 (20%) | ||
| LRR 7 | 202..223 | 6/22 (27%) | |||
| leucine-rich repeat | 203..226 | CDD:275380 | 5/24 (21%) | ||
| LRR 8 | 226..247 | 7/21 (33%) | |||
| leucine-rich repeat | 227..249 | CDD:275380 | 8/22 (36%) | ||
| LRR 9 | 249..270 | 7/20 (35%) | |||
| leucine-rich repeat | 250..273 | CDD:275380 | 8/22 (36%) | ||
| LRR 10 | 273..294 | 0/20 (0%) | |||
| leucine-rich repeat | 274..295 | CDD:275380 | 0/20 (0%) | ||
| LRR | 275..>465 | CDD:227223 | 54/210 (26%) | ||
| LRR 11 | 320..341 | 3/20 (15%) | |||
| leucine-rich repeat | 321..344 | CDD:275378 | 3/22 (14%) | ||
| LRR 12 | 344..365 | 7/24 (29%) | |||
| LRR_8 | 345..401 | CDD:404697 | 22/59 (37%) | ||
| leucine-rich repeat | 345..366 | CDD:275378 | 7/24 (29%) | ||
| LRR 13 | 366..387 | 9/20 (45%) | |||
| leucine-rich repeat | 367..390 | CDD:275378 | 10/22 (45%) | ||
| LRR 14 | 390..411 | 11/20 (55%) | |||
| leucine-rich repeat | 391..414 | CDD:275378 | 13/22 (59%) | ||
| LRR 15 | 414..435 | 6/21 (29%) | |||
| leucine-rich repeat | 415..427 | CDD:275378 | 4/12 (33%) | ||
| leucine-rich repeat | 436..461 | CDD:275380 | 8/40 (20%) | ||
| 7tmA_LGR4 | 539..812 | CDD:320483 | 67/303 (22%) | ||
| TM helix 1 | 541..565 | CDD:320483 | 5/23 (22%) | ||
| TM helix 2 | 574..595 | CDD:320483 | 5/20 (25%) | ||
| TM helix 3 | 619..641 | CDD:320483 | 8/21 (38%) | ||
| TM helix 4 | 664..680 | CDD:320483 | 5/25 (20%) | ||
| TM helix 5 | 704..727 | CDD:320483 | 5/25 (20%) | ||
| TM helix 6 | 746..768 | CDD:320483 | 5/27 (19%) | ||
| TM helix 7 | 780..805 | CDD:320483 | 8/24 (33%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2087 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||