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Protein Alignment Lgr3 and fshr-1

DIOPT Version :9

Sequence 1:	NP_733115.1	Gene:	Lgr3 / 43098	FlyBaseID:	FBgn0039354	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_001263853.1	Gene:	fshr-1 / 179381	WormBaseID:	WBGene00008239	Length:	932	Species:	Caenorhabditis elegans

Alignment Length:	656	Identity:	155/656 - (23%)
Similarity:	264/656 - (40%)	Gaps:	136/656 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 SEVTNLIIIR--NNLTLRDNIFANFTRLQKLTLKYNNISRVPLGSFSGLFH--LERLELSHNNVS 216
            |::..|.:::  |...:...:..|.||:|.:.||.|.::.:|....:...|  |:|::||.|.:.
Worm   132 SKLRKLSVVKCPNLREISGKLLVNNTRIQNVILKNNGLATMPSLRMTDAHHVLLDRIDLSGNKIK 196

  Fly   217 HLPHG---------VFLGLHSL-----------QWLFL-VNNH--LHHLPVEQLRFFRRLEWLVL 258
            .:...         |.|..:.|           |:|.| :||:  |..|.|:..:....|:.|.|
Worm   197 FISDSKVRNVKARTVVLSENKLIEISGYAFTESQFLKLKLNNNPDLRSLSVDAFKNMAGLQTLDL 261

  Fly   259 SRNRL---------TLRNVQLPKIPTLYEV--YLDFNRIE--------------YIGEETFSQLD 298
            |...:         .|:.:.|..:|||..:  .|.|..:|              |:.:.|.:  |
Worm   262 SHTSIDTLPINGLKKLKTLILNDVPTLKSLPSVLSFTDLETAHFTYPHHCCLFKYVDDVTMN--D 324

  Fly   299 NLHLLDLQHNLITHIHGRAFANLTNMRDIRLVGNPIK-ELSGETFLHNTRLEAL--SLALMPIHI 360
            |   ...|.| ...||.|    :.:.|:.:.|....| |.||..||.....|..  |....|...
Worm   325 N---GKYQRN-AKEIHKR----ICDKREQQKVARRRKRETSGIDFLDMLLKEWTDNSTYTGPDDA 381

  Fly   361 SSSLMEPLNISFLNLTGIRYDHIDFEAINSMRNLTYIIYDRFFYCSMTPRVRMCKPSTDGVSSFQ 425
            ....:.|    |:.:.......|..|......|:|                  |.|..|.::..:
Worm   382 DDDELPP----FVEIGAEPCQSIGEEVQKYYSNIT------------------CYPQPDALNPCE 424

  Fly   426 DLLSKPVLRYSAWVMATLTIAGNVLVLWG--RFIYRDENVAVTMVIRNLALADMLMGFYLVTIGV 488
            :::..|.||.:.||:....|.||::| |.  ..:|........:.:.|:::|||:.|.||..:.:
Worm   425 NIVGYPFLRIAVWVVCLAAIVGNIIV-WALLGIVYEKRMRMHYLYMINMSVADMVTGIYLAVLAI 488

  Fly   489 QDYRYRNEYYKVVLDWITSWQCTLIGTLAVSSSEVSMLILAFMSLERFLLIADPFRGHRSIGNRV 553
            .|.:..:|||:..:.|.|.|.|...|.|||.:||:.::.:..::.|........|||.| :..:|
Worm   489 ADAKMSDEYYRHAVWWQTGWGCRAAGFLAVFASELGIISMFLIAFEMSYNTRQSFRGRR-LSPKV 552

  Fly   554 MWLALICIWITGVGLAVAPVLLWRTSTLPYY--GSY--SGTCFPLHIHEAFPMGWLYSAFVF-LG 613
            ..|.:|..|:..:.:|:          ||::  .||  |..|.||.....|...:|    :| |.
Worm   553 GVLLMIGGWLFAIIMAI----------LPWFDVSSYSESSVCLPLRAATIFDKSYL----IFGLS 603

  Fly   614 VNLLLLVMIAMLYTALLISIWR---TRSATPLTLLDCEFAVRFFFIVLTDFLCWVPIIVMKIWVF 675
            .|.|....:|:.| ..::.:.:   ||..      |.....:...:|:||.:||.|.:      |
Worm   604 FNFLAFAAMALSY-GFIVKMLKENETREE------DRALITKMTVLVVTDLICWFPTL------F 655

  Fly   676 FNYN-------ISDDIYAWLVVFVLPLNSAVNPLLYTFTTPKYRNQIFLRGWKKITSRKRAEAGN 733
            |.:.       :|.....:::||..|:|:..||.||.|.|...::::  |. |.:...:|...|.
Worm   656 FGFTATIGFPLLSLSSAKFVLVFFFPINAFANPFLYVFFTEVIQHRV--RS-KTLPVIRRITTGP 717

  Fly   734 GNVATT 739
            .|.|::
Worm   718 LNAASS 723

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.