DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lgr3 and lrrc57

DIOPT Version :9

Sequence 1:NP_733115.1 Gene:Lgr3 / 43098 FlyBaseID:FBgn0039354 Length:765 Species:Drosophila melanogaster
Sequence 2:NP_001120199.1 Gene:lrrc57 / 100145243 XenbaseID:XB-GENE-5779276 Length:238 Species:Xenopus tropicalis


Alignment Length:261 Identity:70/261 - (26%)
Similarity:105/261 - (40%) Gaps:66/261 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   148 LRRFP----RLSSEVTNLIIIRNNLTLRDNIFANFTRLQKLTLKYNNISRVPLGSFSGLFHLERL 208
            |..||    |||..:..:.:..|.:.....:...|..|:.|||..|.|||:| .....|..||.|
 Frog    26 LTEFPEDLQRLSGNLRTIDLSSNKIEALPPMVGKFNLLKSLTLNNNRISRLP-DELCRLKKLETL 89

  Fly   209 ELSHNNVSHLPHGVFLGLHSLQWLFLVNNHLHHLPVEQLRFFRRLEWLVLSRNRLTLRNVQLPKI 273
            .||.|.:|.:| ..|:.|.:|:.|.|..|.|..||                        .||.|:
 Frog    90 HLSGNQISQIP-ADFVQLLALKTLNLSGNQLRTLP------------------------AQLCKL 129

  Fly   274 PTLYEVYLDFNRIEYIGEETFSQLDNLHLLDLQHNLITHI--HGRAFANLTNMRDIRLVGNPIKE 336
            ..|..|.|..|||:.|.:|. |.|..:. |:|..|.|:.|  |   .::...::.:||..|    
 Frog   130 RNLDVVDLSKNRIQAIPDEV-SGLQAIE-LNLNQNQISQISVH---ISHCPRLKVLRLEEN---- 185

  Fly   337 LSGETFLHNTRLEALSLALMPIHISSSLMEPLNISFLNLTGIRYDHIDFEAINSMRNLTYIIYDR 401
                         .|.|:::|    .|::....||.|.:.|..::      |..:|:|..  ||:
 Frog   186 -------------CLELSMLP----QSILGDSQISLLAVEGNLFE------IKKLRDLEG--YDK 225

  Fly   402 F 402
            :
 Frog   226 Y 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lgr3NP_733115.1 LDLa 32..65 CDD:238060
LRR_8 179..239 CDD:290566 24/59 (41%)
leucine-rich repeat 181..204 CDD:275380 10/22 (45%)
LRR_RI <196..354 CDD:238064 41/159 (26%)
leucine-rich repeat 205..228 CDD:275380 10/22 (45%)
leucine-rich repeat 229..252 CDD:275380 7/22 (32%)
leucine-rich repeat 253..275 CDD:275380 3/21 (14%)
LRR_8 274..334 CDD:290566 19/61 (31%)
leucine-rich repeat 276..299 CDD:275380 10/22 (45%)
leucine-rich repeat 300..323 CDD:275380 6/24 (25%)
leucine-rich repeat 324..347 CDD:275380 3/22 (14%)
7tm_1 447..704 CDD:278431
lrrc57NP_001120199.1 LRR <20..>168 CDD:227223 52/169 (31%)
leucine-rich repeat 40..62 CDD:275380 2/21 (10%)
leucine-rich repeat 63..85 CDD:275380 10/22 (45%)
leucine-rich repeat 86..108 CDD:275380 10/22 (45%)
leucine-rich repeat 109..131 CDD:275380 10/45 (22%)
leucine-rich repeat 132..154 CDD:275380 10/22 (45%)
leucine-rich repeat 155..176 CDD:275380 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4149
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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