Protein Alignment RASSF8 and Rassf10

DIOPT Version :10

• Sequence 1: NP_651411.1
• Gene: RASSF8 / 43096
• FlyBaseID: FBgn0261986
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_780488.2
• Gene: Rassf10 / 78748
• MGIID: 1925998
• Length: 508
• Species: Mus musculus
• Alignment Length: 690
• Identity: 115/690 - (16%)
• Similarity: 198/690 - (28%)
• Gaps: 311/690 - (45%)

  Fly     2 ELKVWVEGIQRIVCGVTVNTTCQDVVFALAH---------------------------------- 32
            ::.||:...:::|.|::..|||.|||..|..
Mouse     7 KISVWICQEEKLVSGLSRRTTCSDVVRVLLEDGCRRRCRQRRGQRRGLTEDPSGQLELPEPPDEN 71

  Fly    33 ------------ATGKVGRFTLIERWRNNERHLAPNENPMKLLLKWGEYANDVQFILQRSENKTQ 85
                        ..|....:.::|:||..||.|......::|...||:...:|:|:|.|||...
Mouse    72 DEDDDDAMPPGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWTAWGDEQENVRFVLVRSEASL- 135

  Fly    86 QQQQQQQQQQQNNNNNNNYAVMTTTKKPLGPNNNNNNKPAPTLLKQKSNVELSYRTKELKKSFGG 150
                                          ||....:..|..:|.:
Mouse   136 ------------------------------PNAGPRSAEARVVLSR------------------- 151

  Fly   151 HDAKQFDNIGIVKGIPQQQQLQSQQTAMGAPASPPQEQLTPQDNNNVAPLVPKHEKSLSNPLDMT 215
                                 :....|.||||. |...||.:....|.
Mouse   152 ---------------------ERPCLARGAPAR-PSLALTQEKQRRVV----------------- 177

  Fly   216 STGSNPPAPTNGYNDFYNNNSSSNQHIYSQLSKSSNELRRSSPNEMYYNNNNNIVNNNNNSPELY 280
                                    :..:.:|:| .|..|:..|
Mouse   178 ------------------------RKAFRKLAK-LNRRRQQQP---------------------- 195

  Fly   281 KQTPTISANGALVPPPYRDPPPPRNSPMCQGQRLASSNADTMSNASSSTNPFLSDYDQHSSHNTN 345
                                    :|| |     :|:::.|.|:.|||..          :|.:.
Mouse   196 ------------------------SSP-C-----SSTSSSTASSCSSSAR----------THESA 220

  Fly   346 SINNNSQAMEEGEPMFQTTQYNDLLQLIKFQREKITAQQMELQKFDTEIVYLESK---ERDHAH- 406
            |:    :.||            .|:.|:..|...|..|...|::.|.||...|:|   :|...|
Mouse   221 SV----ERME------------TLVHLVLSQDHTIRQQVQRLRELDREIDRYEAKVHLDRMRRHG 269

  Fly   407 --------------ELDAISREISKADQIFRQ-GSEQLQTLQYVEEENELVKQQEKTLKSEIALL 456
                          :||..:.|....|....: |:|....|.         .:.:.....|:|..
Mouse   270 VNYVQDTYLVGAGIDLDGQTPEGEPEDATLEEKGTEPAAPLD---------SEAQAAALEELARR 325

  Fly   457 RSKLANCETELLQCKNKMRLLMDDI--ELEQQHQQQTNRQTVER------------DFLMEMERI 507
            ...|...:.|..|.:..:..|..:|  ||.|:..|:.|.:...|            :.|:|.||:
Mouse   326 CDDLVRLQEERAQQEELLERLSAEIQEELNQRWMQRRNEELAAREESLEPDGGPDGELLLEQERV 390

  Fly   508 QSEIDQALH-----NTDTSNKTADSLKKELLMIEHAIADKKRQVEQLVNEMKEVNLQSLTVTTTE 567
            ::::..:|:     :||     .:::|.:|...:.....|:|:::.|        ||||. |..:
Mouse   391 RTQLSTSLYIGLRLSTD-----LEAVKADLDYSQQQRDIKERELQGL--------LQSLH-TFEQ 441

  Fly   568 EIKHLLEG----------PNKQGSSRRIIGSPRQLETAVP 597
            .:.|  :|          |..|..:...:...|.|..:.|
Mouse   442 TVVH--DGALGSSGPSREPQPQTCAEMWVDQARGLAKSCP 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_651411.1	RA_RASSF8	2..83	CDD:340551	27/126 (21%)
		DR0291	386..>556	CDD:441187	40/207 (19%)
Rassf10	NP_780488.2	RA_RASSF10	7..134	CDD:340549	27/126 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..81		0/29 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..221		14/97 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	473..508		2/7 (29%)