Protein Alignment RASSF8 and Rassf8

DIOPT Version :9

• Sequence 1: NP_651411.1
• Gene: RASSF8 / 43096
• FlyBaseID: FBgn0261986
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_082036.1
• Gene: Rassf8 / 71323
• MGIID: 1918573
• Length: 419
• Species: Mus musculus
• Alignment Length: 630
• Identity: 141/630 - (22%)
• Similarity: 236/630 - (37%)
• Gaps: 234/630 - (37%)

  Fly     1 MELKVWVEGIQRIVCGVTVNTTCQDVVFALAHATGKVGRFTLIERWRNNERHLAPNENPMKLLLK 65
            |||||||:|:||||||||..||||:||.|||.|.|:.||:||||:||:.||||||:|||:..|.|
Mouse     1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNK 65

  Fly    66 WGEYANDVQFILQRSENKTQQQQQQQQQQQQNNNNNNNYAVMTTTKKPLGPNNNNNNKPAPTLLK 130
            ||:||:|||.||:|:                                  ||:
Mouse    66 WGQYASDVQLILRRT----------------------------------GPS------------- 83

  Fly   131 QKSNVELSYRTKELKKSFGGHDAKQFDNIGIVKGIPQQQQLQSQQTAMGAPASPPQEQLTPQDNN 195
                  ||.|...             |:   |..||::        .:...:.||..:|.||.:.
Mouse    84 ------LSERPTS-------------DS---VARIPER--------TLYRQSLPPLAKLRPQADK 118

  Fly   196 NVAPLVPKHEKSLSNPLDMTSTGSNPPAPTNGYNDFYNNNSSS--NQHIYSQLSKSSNELRRSSP 258
            ::....|| .|||      |.||.     ..|..|.:.....:  .|.:.|....::.||:|
Mouse   119 SIRRREPK-RKSL------TFTGG-----AKGLTDIFGKGKETEFRQKVLSNCRATAEELKR--- 168

  Fly   259 NEMYYNNNNNIVNNNNNSPELYKQTPTISANGALVPPPYRDPPPPRNSPMCQGQRLASSNADTMS 323
                                                                             
Mouse   169 ----------------------------------------------------------------- 168

  Fly   324 NASSSTNPFLSDYDQHSSHNTNSINNNSQAMEEGEPMFQTTQYNDLLQLIKFQREKITAQQMELQ 388
                                                            ||:.|..|:.|.:.:|:
Mouse   169 ------------------------------------------------LIRLQTGKLQAIEKQLE 185

  Fly   389 KFDTEIVYLESKERDHAHELDAISREISKADQIFRQGSEQLQTLQYVEEENELVKQQEKTLKSEI 453
            ..:.||.:.|.|..      .::..||.:.:|..::...:::..::.|.|.::.::.||.|:.::
Mouse   186 SSEAEIRFWEQKYS------CSLEEEIVRLEQRIKRNDVEIEEEEFWENELQIEQENEKQLQDQL 244

  Fly   454 ALLRSKLANCETELLQCKNKMRLLMDDIELEQQHQQQTNRQTVERDFLMEMERIQSEIDQALHNT 518
            ..:|.|:.:||..|.....::..:...::.|:.|::....|..|.:...::|:::.|:|.....:
Mouse   245 EEIRQKVTDCEGRLKDYLAQIHTMESGLQAEKLHREVQEAQVNEEEVKGKIEKVKGEMDLQGQQS 309

  Fly   519 DTSNKTADSLKKELLMIEHAIADKKRQVEQLVNEMKEVNLQSLTVTTTEEIKHL----------- 572
            ........::::.|......:.||::::|||..|:::||||.....|..::..|
Mouse   310 LRLENGIRAVERSLGQATKRLQDKEQELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPTEIEASQ 374

  Fly   573 ----LEGP------NKQGSSRRIIGSPRQLETAVPTSKNPHGVWV 607
                .|.|      .:.||||::..:.|.|:..|.:..||.|::|
Mouse   375 ADIETEAPFQSGSLKRPGSSRQLPSNLRILQNPVSSGFNPEGIYV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_651411.1	UBQ	1..81	CDD:294102	56/79 (71%)
Rassf8	NP_082036.1	RA_RASSF8	2..83	CDD:340551	56/114 (49%)
		Smc	109..>380	CDD:224117	61/404 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..399		6/26 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837021
Domainoid	1	1.000	120	1.000	Domainoid score	I5744
eggNOG	1	0.900	-	-		E1_KOG1574
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3686
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002327
OrthoInspector	1	1.000	-	-		otm42573
orthoMCL	1	0.900	-	-		OOG6_107963
Panther	1	1.100	-	-	O	PTHR15286
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5141
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.750