Protein Alignment RASSF8 and rassf7b

DIOPT Version :10

• Sequence 1: NP_651411.1
• Gene: RASSF8 / 43096
• FlyBaseID: FBgn0261986
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_922933.1
• Gene: rassf7b / 368288
• ZFINID: ZDB-GENE-030429-1
• Length: 427
• Species: Danio rerio
• Alignment Length: 649
• Identity: 132/649 - (20%)
• Similarity: 234/649 - (36%)
• Gaps: 280/649 - (43%)

  Fly     1 MELKVWVEGIQRIVCGVTVNTTCQDVVFALAHATGKVGRFTLIERWRNNERHLAPNENPMKLLLK 65
            |||||||:||.|:|||::.:|:|||||.|||.|.|:.||:.||::.|:.||.|..||.|::.|.|
Zfish     1 MELKVWVDGIPRVVCGLSEDTSCQDVVIALAQAIGQTGRYVLIQKLRDKERQLMANECPLEALAK 65

  Fly    66 WGEYANDVQFILQRSENKTQQQQQQQQQQQQNNNNNNNYAVMTTTKKPLGPNNNNNNKPAPTLLK 130
            .|:..|:|||||:|:...|.:...|.:                                ||.:.|
Zfish    66 LGQLGNEVQFILRRTGPTTSEAPDQSR--------------------------------APKIHK 98

  Fly   131 QKSNVELSYRTKELKKSFGGHDAKQFDNIGIVKGIPQQQQLQSQQTAMGAPASPPQEQLTPQDNN 195
            ....|.:.:  ||.||      |..| |:|                    |::.|:.:
Zfish    99 PTDPVPIKH--KEPKK------ALTF-NLG--------------------PSTSPRTR------- 127

  Fly   196 NVAPLVPKHEKSLSNPLDMTSTGSNPPAPTNGYNDFYNNNSSSNQHIYSQLSKSSNELRRSSPNE 260
                 |.:.||.   |.|..:.|::|                          ..|:.|.:::|::
Zfish   128 -----VKQVEKP---PKDFQARGASP--------------------------SPSSSLAQAAPSK 158

  Fly   261 MYYNNNNNIVNNNNNSPELYKQTPTISANGALVPPPYRDPPPPRNSPMCQGQRLASSNADTMSNA 325
                            ..||:|
Zfish   159 ----------------DALYQQ------------------------------------------- 164

  Fly   326 SSSTNPFLSDYDQHSSHNTNSINNNSQAMEEGEPMFQTTQYNDLLQLIKFQREKITAQQMELQKF 390
                                                           |..|:.::.:.|.:|:.|
Zfish   165 -----------------------------------------------ILRQQGQLQSLQAQLEGF 182

  Fly   391 DTEI-VYLESKERDHAHELDAISREISKADQIFRQGSEQLQTLQYVEEENELVKQQEKTLKSEIA 454
            :.|: |:..|.....:.||   ..|:.:..|.||:...:|...::.|:|.:...|:||
Zfish   183 ERELGVWERSPPPALSPEL---LEEMDRLQQAFRRSEAELAHAKFWEDEFQSEVQKEK------- 237

  Fly   455 LLRSKLANCETELLQCKNKMRLLMDDIELEQQHQQQTNRQTVERDF--LMEMER-----IQSEID 512
                       ::||.||::::.:|. :..:.|...:..:.::|:.  |:|.:|     ::..::
Zfish   238 -----------DILQQKNELKIALDK-QNRRLHDTDSQSEQLQREIQVLIETKRNGMLLVKPSVE 290

  Fly   513 QAL------------HNTD--TSNKTADSLKKELLMIEHAIADKKRQVEQLVNEMKEVNLQSLTV 563
            :::            |..:  ||.:..|   |.|.:.|..:..|.:::|.|..|:::.|||....
Zfish   291 ESVVKAKEQLVNHQRHGAELQTSFEEVD---KALRLAEEELQAKSKELEDLNKELRQCNLQQFIQ 352

  Fly   564 TT----------TEEIKHLLEGP---------------NKQGSSRRIIGSPRQLETAVPTSKNP 602
            .|          |||:...|..|               |.:.::::|:|:||.|:..:.:|.:|
Zfish   353 QTGVTPAQSSQQTEEMDFALLKPDGQSDEDSTSSILEFNPRTTAKQILGNPRSLQNPLVSSLHP 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_651411.1	RA_RASSF8	2..83	CDD:340551	44/80 (55%)
		DR0291	386..>556	CDD:441187	38/191 (20%)
rassf7b	NP_922933.1	RA_RASSF7	1..83	CDD:340552	45/81 (56%)
		Smc	<173..>344	CDD:440809	39/195 (20%)