Protein Alignment RASSF8 and LOC100003291

DIOPT Version :9

• Sequence 1: NP_651411.1
• Gene: RASSF8 / 43096
• FlyBaseID: FBgn0261986
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_001342892.4
• Gene: LOC100003291 / 100003291
• -ID: -
• Length: 444
• Species: Danio rerio
• Alignment Length: 640
• Identity: 149/640 - (23%)
• Similarity: 248/640 - (38%)
• Gaps: 229/640 - (35%)

  Fly     1 MELKVWVEGIQRIVCGVTVNTTCQDVVFALAHATGKVGRFTLIERWRNNERHLAPNENPMKLLLK 65
            |||||||:|:||:|||||..||||:||.|||.|.|:.||:||||:||:.||||.|:|:|:..|..
Zfish     1 MELKVWVDGVQRVVCGVTEATTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLVPHESPVASLNT 65

  Fly    66 WGEYANDVQFILQRSENKTQQQQQQQQQQQQNNNNNNNYAVMTTTKKPLGPNNNNNNKPAPTLLK 130
            ||:||.||||||.|:                 ..:.|.|.. ...:.||||....:.:..|.:.|
Zfish    66 WGQYAGDVQFILHRT-----------------GPSLNEYPT-AECQTPLGPERGLHRQSLPLMAK 112

  Fly   131 QKSNVELSYRTKELKKSFGGHDAKQFDNIGIVKGIPQQQQLQSQQTAMGAPASPPQEQLTPQDNN 195
            .::..:.|.|.:|                      |:::.|    |..|.|
Zfish   113 LRAPGDRSLRRRE----------------------PRRKSL----TFTGVP-------------- 137

  Fly   196 NVAPLVPKHEKSLSNPLDMTSTGSNPPAPTNGYNDFYNNNSSSNQHIYSQLSKSSNELRRSSPNE 260
                      :||.   |:.|.|                          :||.||...|..
Zfish   138 ----------RSLR---DILSGG--------------------------RLSDSSARQREV---- 159

  Fly   261 MYYNNNNNIVNNNNNSPELYKQTPTISANGALVPPPYRDPPPPRNSPMCQGQRLASSNADTMSNA 325
                    :|.:.:|||.:                          ||...|.|:
Zfish   160 --------LVRSASNSPAV--------------------------SPRLSGNRI----------- 179

  Fly   326 SSSTNPFLSDYDQHSSHNTNSINNNSQAMEEGEPMFQTTQYNDLLQLIKFQREKITAQQMELQKF 390
                                                     .||.||::.|||.::.....::.:
Zfish   180 -----------------------------------------EDLTQLVRLQRETLSVLDGRMEAY 203

  Fly   391 DTEI-------VYLESKERDHAHELDAISREISKADQIFRQGSEQLQTLQYVEEENELVKQQEKT 448
            :.::       |.||..|.     ...::.|:|:.::..|:...:::..::...|.::..:.|:.
Zfish   204 EADLRMLTEKRVGLEDNEM-----FVKLTEEVSRLEKQVRRNKVEIEEEEFWATELQIELESERQ 263

  Fly   449 LKSEIALLRSKLANCETELLQCKNKMRLLMD---DIELEQQHQQ-QTNRQTVERDFLMEMERIQS 509
            |:..|..|..:|..||.:|.|   :||.|..   .||.::||:: :..:|..|.:....::|.::
Zfish   264 LQERIQELSGRLRGCEVDLEQ---RMRTLQGVEAGIETQRQHKEIRETQQASEGEVKARLQRAKA 325

  Fly   510 EID-QALHNTDTSNKTADSLKKELLMIEHAIADKKRQVEQLVNEMKEVNLQSLTVTTTEEIKHLL 573
            |:. ||.|:....| ::.::.:.|......:.:.:.::|||..|:::||||.....|..::..|.
Zfish   326 ELKVQAQHSAQIEN-SSRAVDRSLTESCRRLQESQYELEQLTKELRQVNLQQFIQQTGTKVTVLP 389

  Fly   574 EGPNKQ---------------GSSRR------IIGSPRQLETAVPTSKNPHGVWV 607
            ..|..:               ||.:|      ::||.|.|.:.:....||.|::|
Zfish   390 VEPGDEESSSTTGDKDFAALTGSLKRPSLSHPVVGSIRGLHSPISAGLNPEGIYV 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_651411.1	UBQ	1..81	CDD:294102	53/79 (67%)
LOC100003291	XP_001342892.4	RA	1..81	CDD:214612	53/96 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580555
Domainoid	1	1.000	123	1.000	Domainoid score	I5533
eggNOG	1	0.900	-	-		E1_KOG1574
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H138283
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3689
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1442074at2759
OrthoFinder	1	1.000	-	-		FOG0002327
OrthoInspector	1	1.000	-	-		otm24397
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4258
SonicParanoid	1	1.000	-	-		X5141
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.890