Protein Alignment RASSF8 and rassf8a

DIOPT Version :10

• Sequence 1: NP_651411.1
• Gene: RASSF8 / 43096
• FlyBaseID: FBgn0261986
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_073799382.1
• Gene: rassf8a / 100003291
• ZFINID: ZDB-GENE-091014-4
• Length: 491
• Species: Danio rerio
• Alignment Length: 687
• Identity: 153/687 - (22%)
• Similarity: 251/687 - (36%)
• Gaps: 276/687 - (40%)

  Fly     1 MELKVWVEGIQRIVCGVTVNTTCQDVVFALAHATGKVGRFTLIERWRNNERHLAPNENPMKLLLK 65
            |||||||:|:||:|||||..||||:||.|||.|.|:.||:||||:||:.||||.|:|:|:..|..
Zfish     1 MELKVWVDGVQRVVCGVTEATTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLVPHESPVASLNT 65

  Fly    66 WGEYANDVQFILQRSENKTQQQQQQQQQQQQNNNNNNNYAVMTTTKKPLGPNNNNNNKPAPTLLK 130
            ||:||.||||||.|:                 ..:.|.|.. ...:.||||....:.:..|.:.|
Zfish    66 WGQYAGDVQFILHRT-----------------GPSLNEYPT-AECQTPLGPERGLHRQSLPLMAK 112

  Fly   131 QKSNVELSYRTKELKKSFGGHDAKQFDNIGIVKGIPQQQQLQSQQTAMGAPASPPQEQLTPQDNN 195
            .::..:.|.|.:|                      |:::.|    |..|.|
Zfish   113 LRAPGDRSLRRRE----------------------PRRKSL----TFTGVP-------------- 137

  Fly   196 NVAPLVPKHEKSLSNPLDMTSTGSNPPAPTNGYNDFYNNNSSSNQHIYSQLSKSSNELRRSSPNE 260
                      :||.   |:.|.|                          :||.||...|..
Zfish   138 ----------RSLR---DILSGG--------------------------RLSDSSARQREV---- 159

  Fly   261 MYYNNNNNIVNNNNNSPELYKQTPTISANGALVPPPYRDPPPPRNSPMCQGQRLASSNADTMSNA 325
                    :|.:.:|||.:                          ||...|.|:
Zfish   160 --------LVRSASNSPAV--------------------------SPRLSGNRI----------- 179

  Fly   326 SSSTNPFLSDYDQHSSHNTNSINNNSQAMEEGEPMFQTTQYNDLLQLIKFQREKITAQQMELQKF 390
                                                     .||.||::.|||.::.....::.:
Zfish   180 -----------------------------------------EDLTQLVRLQRETLSVLDGRMEAY 203

  Fly   391 DTEI-------VYLESKERDHAHELDAISREISKADQIFRQGSEQLQTLQYVEEENELVKQQEKT 448
            :.::       |.||..|.     ...::.|:|:.::..|:...:::..::...|.::..:.|:.
Zfish   204 EADLRMLTEKRVGLEDNEM-----FVKLTEEVSRLEKQVRRNKVEIEEEEFWATELQIELESERQ 263

  Fly   449 LKSEIALLRSKLANCETELLQCKNKMRLLMD---DIELEQQHQQ-QTNRQTVERDFLMEMERIQS 509
            |:..|..|..:|..||.:|.|   :||.|..   .||.::||:: :..:|..|.:....::|.::
Zfish   264 LQERIQELSGRLRGCEVDLEQ---RMRTLQGVEAGIETQRQHKEIRETQQASEGEVKARLQRAKA 325

  Fly   510 EID-QALHNTDTSNKTADSLKKELLMIEHAIADKKRQVEQLVNEMKEVNLQ--------SLTVTT 565
            |:. ||.|:....| ::.::.:.|......:.:.:.::|||..|:::||||        .:||..
Zfish   326 ELKVQAQHSAQIEN-SSRAVDRSLTESCRRLQESQYELEQLTKELRQVNLQQFIQQTGTKVTVLP 389

  Fly   566 TEE------------------------------------------IKHLLE-------------- 574
            .|.                                          :|.||.
Zfish   390 VEPGDEESSSTTGDKGTAFIDNKSKAPTSNSLWWLRVAPCSLIDFLKSLLRYLFSLFSFISSDFA 454

  Fly   575 ---GPNKQGS-SRRIIGSPRQLETAVPTSKNPHGVWV 607
               |..|:.| |..::||.|.|.:.:....||.|::|
Zfish   455 ALTGSLKRPSLSHPVVGSIRGLHSPISAGLNPEGIYV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_651411.1	RA_RASSF8	2..83	CDD:340551	52/80 (65%)
		DR0291	386..>556	CDD:441187	37/181 (20%)
rassf8a	XP_073799382.1	None