DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tnks and AT1G07710

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_001318946.1	Gene:	AT1G07710 / 837285	AraportID:	AT1G07710	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	114/507 - (22%)
Similarity:	181/507 - (35%)	Gaps:	172/507 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 DTPLHLAVVSPDGKRKQLMELLTRK-----GSLLNEKNKAFLTPLHLAAELLHYDAMEVLLKQGA 423
            ||.||.||  ..|.:.:::|:||:.     ..||.::|::..|.|::|||   |..:|::.:.
plant    28 DTLLHSAV--RHGNKDRVVEILTKTRESELNQLLGKQNQSGETALYVAAE---YGDVEIVKEM-- 85

  Fly   424 KVNALDSLGQTPLHRCARDEQAVRLLLSYAADTNIVSLEGLTAAQLASDSVLKLLKNPPDSETHL 488
             :|..|                       .|...|.:..|..|..:
plant    86 -INCYD-----------------------LALVEIKARNGFDAFHI------------------- 107

  Fly   489 LEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLEHGAEVYA-ADKG 552
              |||.||||.::  ||....|.....:|..::|.||.||......||.||||.|:.:.. |...
plant   108 --AAKQGDLDVLK--VLAEAHSELAMTVDLSNTTALHTAATQGHTEVVNFLLELGSSLAGIAKSN 168

  Fly   553 GLVPLHNACSYGHYEVTELLVKHGANVNVSDLWKFTPLHEAAAKGKYDICKLLLKHGADPMKKNR 617
            |...||:|...||.:|.:.|:
plant   169 GKTALHSASRNGHVKVIKALL-------------------------------------------- 189

  Fly   618 DGATPADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPE--SINCRDAQGRNSTPLHLA 680
             .:.||..::...       :|.:||..|.|..|:..|:.|:..:  |||..|.:|  :|.||:|
plant   190 -ASEPAIAIRMDK-------KGQTALHMAVKGTNVEVVEELIKADRSSINIADTKG--NTALHIA 244

  Fly   681 AGYNNFECAEYLLENG-ADVNAQDKGGLIPLHNASSYGHLDIAALLIKH-----KTVVNATDKWG 739
            |.....:..:.||.|. .|..|.::.|...|..|...|:.::|.:|.||     ||:..:    |
plant   245 ARKGRSQIVKLLLANNMTDTKAVNRSGETALDTAEKIGNPEVALILQKHGVPSAKTIKPS----G 305

  Fly   740 FTPLHEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELATADDVKCLLQDAMA-TSLSQQALSA 803
            ..|..|..|                               |..|:|..:.:.:. |.|:::.:..
plant   306 PNPARELKQ-------------------------------TVSDIKHEVHNQLEHTRLTRKRVQG 339

  Fly   804 STQSLTSSSPAPDATAAAAPGTSSSSSSAILSPTTETVLLPTGA-SMILSVP 854
            ..:.|....             :...::||.|.|...||:.|.| :.|.:||
plant   340 IAKQLNKMH-------------TEGLNNAINSTTVVAVLIATVAFAAIFTVP 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnks	NP_001262963.1	ANK	49..163	CDD:238125
		ANK repeat	59..87	CDD:293786
		Ank_2	61..153	CDD:289560
		ANK repeat	89..120	CDD:293786
		ANK repeat	122..153	CDD:293786
		ANK	202..316	CDD:238125
		ANK repeat	212..240	CDD:293786
		Ank_2	214..306	CDD:289560
		ANK repeat	242..273	CDD:293786
		ANK repeat	275..306	CDD:293786
		ANK	361..478	CDD:238125	26/118 (22%)
		ANK repeat	363..396	CDD:293786	12/36 (33%)
		Ank_2	367..459	CDD:289560	21/96 (22%)
		ANK	393..573	CDD:238125	45/180 (25%)
		ANK repeat	398..429	CDD:293786	8/30 (27%)
		ANK repeat	431..459	CDD:293786	1/27 (4%)
		ANK repeat	483..515	CDD:293786	10/31 (32%)
		Ank_4	486..540	CDD:290365	19/53 (36%)
		ANK	512..637	CDD:238125	24/125 (19%)
		ANK repeat	522..550	CDD:293786	12/28 (43%)
		Ank_2	524..616	CDD:289560	20/92 (22%)
		ANK repeat	552..583	CDD:293786	8/30 (27%)
		ANK repeat	585..610	CDD:293786	0/24 (0%)
		ANK repeat	638..668	CDD:293786	11/31 (35%)
		Ank_4	641..693	CDD:290365	17/53 (32%)
		ANK	665..779	CDD:238125	27/119 (23%)
		ANK repeat	672..703	CDD:293786	10/31 (32%)
		Ank_2	677..769	CDD:289560	23/97 (24%)
		ANK repeat	705..736	CDD:293786	10/35 (29%)
		ANK repeat	738..769	CDD:293786	4/30 (13%)
		SAM_tankyrase1,2	887..952	CDD:188923
		SAM	890..952	CDD:197735
		tankyrase_like	948..1170	CDD:238718
		PARP	961..1165	CDD:279038
AT1G07710	NP_001318946.1	ANK repeat	26..63	CDD:293786	12/36 (33%)
		Ank_2	31..127	CDD:372319	34/149 (23%)
		ANK repeat	65..98	CDD:293786	11/61 (18%)
		ANK repeat	100..132	CDD:293786	12/54 (22%)
		ANKYR	108..312	CDD:223738	69/263 (26%)
		ANK repeat	134..166	CDD:293786	12/31 (39%)
		ANK repeat	168..200	CDD:293786	10/76 (13%)
		ANK repeat	202..234	CDD:293786	11/31 (35%)
		ANK repeat	270..294	CDD:293786	7/23 (30%)
		PGG	349..466	CDD:372845	11/30 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8400
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000