DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tnks and AT1G05640

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_172055.1	Gene:	AT1G05640 / 837070	AraportID:	AT1G05640	Length:	627	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	128/495 - (25%)
Similarity:	210/495 - (42%)	Gaps:	92/495 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 RKGSLLNEKNKAFLTPLHLAAELLHYDAMEVLLKQGAKVNALDSLGQTPLHRCARDEQAVRLLLS 451
            |||..| :|..:||             |:.|:.|.|.|..|::.     ..|....:::.|..:.
plant    35 RKGRAL-DKQVSFL-------------AVNVVEKHGIKGRAMEK-----QERAMERQRSFRGFVE 80

  Fly   452 YAADTNIVSLEGLTAAQLASDSVLKLLKNPP----DSETHLLEAAKAGDLDTVRRIV-LNNPISV 511
            ......:|....|:...:..:.  |...:.|    ||..||  ||:.|:|..|..:: ..|.|.
plant    81 KQKSFRVVMERQLSFMNVGGER--KKKTDSPGKRGDSPLHL--AARTGNLGKVMELIRACNGIE- 140

  Fly   512 NCRDLDGRHS----TPLHFAAGFNRVPVVQFLLEH----GAEVYAADKGGLVPLHNACSYGHYEV 568
            ..::|..:.:    |||:.||......||:.:|:|    .|.|.|  :.|..|.|.|...||.|.
plant   141 ELKELSSKQNLEGETPLYSAAENGHSLVVEEMLKHMDLDTASVKA--RNGFDPFHVAAKQGHIEA 203

  Fly   569 TELLVKHGANVNVS-DLWKFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHD 632
            .:.|::...|:.:: ||...|.||.||::|..|:..||||                     :|..
plant   204 LKKLLETFPNLAMTVDLSCTTALHTAASQGHTDVVNLLLK---------------------TDSH 247

  Fly   633 VAELLR--GPSALLDAAKKGNLARVQRLV-TPESINCR-DAQGRNSTPLHLAA-GYNNFECAEYL 692
            :|::.:  |.:||..||:.|:...|:.|: ...||..| |.:|:  |.||:|. |.|.....|.:
plant   248 LAKIAKNNGKTALHSAARMGHREVVKSLIGNDASIGFRTDKKGQ--TALHMAVKGQNEGIVLELV 310

  Fly   693 LENGADVNAQDKGGLIPLHNASSYGHLDIAALLIKHKTV-VNATDKWGFTPLHEAAQKGRTQLCS 756
            ..:.|.::.:|..|..|||.|::.|.:.|...|:....: :||.:|.|.|.|..|.:.|..:|.|
plant   311 KPDPAILSVEDSKGNTPLHTATNKGRIKIVRCLVSFDGINLNAMNKAGDTALDIAEKIGNPELVS 375

  Fly   757 LLLAHGADAYMKNQEGQTPIEL--ATADDVK----CLLQDAMATSLSQQALSASTQSLTSSSPAP 815
            :|...||.......:.:.|.:.  .|..|:|    ..||.:..|.:..:.::...:.|
plant   376 VLKEAGAATAKDLGKPRNPAKQLNQTVSDIKHEVQSQLQQSRQTGVRVRRIAKRLKKL------- 433

  Fly   816 DATAAAAPGTSSSSSSAILSPTTETVLLPTGA-SMILSVP 854
                     ..:..::||.|.|...||:.|.| :.|.::|
plant   434 ---------HINGLNNAINSATVVAVLIATVAFAAIFTIP 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnks	NP_001262963.1	ANK	49..163	CDD:238125
		ANK repeat	59..87	CDD:293786
		Ank_2	61..153	CDD:289560
		ANK repeat	89..120	CDD:293786
		ANK repeat	122..153	CDD:293786
		ANK	202..316	CDD:238125
		ANK repeat	212..240	CDD:293786
		Ank_2	214..306	CDD:289560
		ANK repeat	242..273	CDD:293786
		ANK repeat	275..306	CDD:293786
		ANK	361..478	CDD:238125	18/90 (20%)
		ANK repeat	363..396	CDD:293786	4/8 (50%)
		Ank_2	367..459	CDD:289560	15/71 (21%)
		ANK	393..573	CDD:238125	46/192 (24%)
		ANK repeat	398..429	CDD:293786	8/30 (27%)
		ANK repeat	431..459	CDD:293786	2/27 (7%)
		ANK repeat	483..515	CDD:293786	11/32 (34%)
		Ank_4	486..540	CDD:290365	17/58 (29%)
		ANK	512..637	CDD:238125	37/133 (28%)
		ANK repeat	522..550	CDD:293786	12/31 (39%)
		Ank_2	524..616	CDD:289560	32/96 (33%)
		ANK repeat	552..583	CDD:293786	9/31 (29%)
		ANK repeat	585..610	CDD:293786	11/24 (46%)
		ANK repeat	638..668	CDD:293786	11/33 (33%)
		Ank_4	641..693	CDD:290365	19/54 (35%)
		ANK	665..779	CDD:238125	34/118 (29%)
		ANK repeat	672..703	CDD:293786	8/31 (26%)
		Ank_2	677..769	CDD:289560	29/93 (31%)
		ANK repeat	705..736	CDD:293786	10/31 (32%)
		ANK repeat	738..769	CDD:293786	10/30 (33%)
		SAM_tankyrase1,2	887..952	CDD:188923
		SAM	890..952	CDD:197735
		tankyrase_like	948..1170	CDD:238718
		PARP	961..1165	CDD:279038
AT1G05640	NP_172055.1	ANK repeat	112..150	CDD:293786	12/40 (30%)
		Ank_2	117..209	CDD:403870	30/96 (31%)
		ANK repeat	152..185	CDD:293786	11/32 (34%)
		ANK repeat	187..219	CDD:293786	9/31 (29%)
		ANKYR	191..413	CDD:223738	70/244 (29%)
		Ank_2	192..285	CDD:403870	32/113 (28%)
		ANK repeat	221..253	CDD:293786	13/52 (25%)
		ANK repeat	255..287	CDD:293786	11/31 (35%)
		ANK repeat	289..321	CDD:293786	9/33 (27%)
		ANK repeat	323..355	CDD:293786	10/31 (32%)
		PGG	435..550	CDD:404788	10/30 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8400
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000