DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnks and ANK1

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_001331981.1 Gene:ANK1 / 831855 AraportID:AT5G02620 Length:547 Species:Arabidopsis thaliana


Alignment Length:464 Identity:111/464 - (23%)
Similarity:179/464 - (38%) Gaps:109/464 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   519 RHSTPLHFAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSD 583
            |..||||.|.   |......|||            ::..|:.     .|:.|||.:...:..   
plant    16 RDDTPLHTAV---REGKTDLLLE------------MIGEHDG-----VELKELLAEQNQSGE--- 57

  Fly   584 LWKFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHDVA--ELLRGPSALLDA 646
                |.|:.||..|..|:.|:|:||                    ||..:|  :...|..|...|
plant    58 ----TALYVAAEYGYTDMVKILMKH--------------------SDSVLAGTKAKNGFDAFHIA 98

  Fly   647 AKKGNLARVQRLV--TPESINCRDAQGRNSTPLHLAAGYNNFECAEYLLENGADVNA-QDKGGLI 708
            ||.|||..:..|:  .||.....|:.  .:|.||.||...:.|...:||:.|.|:.| ....|..
plant    99 AKNGNLQVLDVLIEANPELSFTFDSS--KTTALHTAASQGHGEIVCFLLDKGVDLAAIARSNGKT 161

  Fly   709 PLHNASSYGHLDIAALLIKHKT-VVNATDKWGFTPLHEAAQKGRTQLCSLLL-AHGADAYMKNQE 771
            .||:|:..||..|...||:.|. :|...||.|.|.||.|.:...|::..:|: |.|:.....:.:
plant   162 ALHSAARNGHTVIVKKLIEKKAGMVTRVDKKGQTALHMAVKGQNTEIVDVLMEADGSLINSADNK 226

  Fly   772 GQTPIELATADDVKCLLQDAMATSLSQQALSASTQSLTSSSPAPDATAAAAPGTSSSSSSAILSP 836
            |.||:.:|...:...::.|........|.|.:...||............:....:.|..:|:   
plant   227 GNTPLHIAVRKNRAEVIVDQSFKLFLLQKLESFLYSLQIVQTVLKYCEVSRVAVNKSGETAL--- 288

  Fly   837 TTETVLLPTGASMILSVPVPLPLSSSTRISPAQGAEANGAEGSSSDDLLPDADTITNVSGFLSSQ 901
               .:...||...|:.:...:.:.::..|.||:..|.:|                       ||:
plant   289 ---DIAEKTGLHEIVPLLQKIGMQNARSIKPAEKVEPSG-----------------------SSR 327

  Fly   902 QLHHLIELFEREQITLDILAEMGHD---DLKQVGVSAYGFRHKILKGIAQ---LRSTTGIGNNVN 960
            :|.             :.::|:||:   .|:|.|.:     .:.::|||:   ...|.|:.|.:|
plant   328 KLK-------------ETVSEIGHEVHTQLEQTGRT-----RREIQGIAKRVNKMHTEGLNNAIN 374

  Fly   961 LCTLLVDLL 969
            ..||:..|:
plant   375 STTLVAILI 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125
ANK repeat 212..240 CDD:293786
Ank_2 214..306 CDD:289560
ANK repeat 242..273 CDD:293786
ANK repeat 275..306 CDD:293786
ANK 361..478 CDD:238125
ANK repeat 363..396 CDD:293786
Ank_2 367..459 CDD:289560
ANK 393..573 CDD:238125 14/53 (26%)
ANK repeat 398..429 CDD:293786
ANK repeat 431..459 CDD:293786
ANK repeat 483..515 CDD:293786
Ank_4 486..540 CDD:290365 7/20 (35%)
ANK 512..637 CDD:238125 28/119 (24%)
ANK repeat 522..550 CDD:293786 9/27 (33%)
Ank_2 524..616 CDD:289560 22/91 (24%)
ANK repeat 552..583 CDD:293786 5/30 (17%)
ANK repeat 585..610 CDD:293786 10/24 (42%)
ANK repeat 638..668 CDD:293786 11/31 (35%)
Ank_4 641..693 CDD:290365 17/53 (32%)
ANK 665..779 CDD:238125 37/116 (32%)
ANK repeat 672..703 CDD:293786 11/31 (35%)
Ank_2 677..769 CDD:289560 32/94 (34%)
ANK repeat 705..736 CDD:293786 11/31 (35%)
ANK repeat 738..769 CDD:293786 9/31 (29%)
SAM_tankyrase1,2 887..952 CDD:188923 12/70 (17%)
SAM 890..952 CDD:197735 12/67 (18%)
tankyrase_like 948..1170 CDD:238718 7/25 (28%)
PARP 961..1165 CDD:279038 3/9 (33%)
ANK1NP_001331981.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8400
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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