DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tnks and AT2G24600

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_001189592.1 Gene:AT2G24600 / 816996 AraportID:AT2G24600 Length:601 Species:Arabidopsis thaliana


Alignment Length:574 Identity:124/574 - (21%)
Similarity:192/574 - (33%) Gaps:204/574 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 DAVMAND--PLRELFEACKTGEIAKVKKLITPQTVNARDTAGRKSTPLHFAAGYGRREVVEFLLN 78
            ||::.||  ....|.||.:    :.:::....|..|        :|.||.||..|.||:|     
plant     6 DAILQNDLPAFLGLVEARE----SSLEERSEEQNTN--------NTVLHVAAKLGHRELV----- 53

  Fly    79 SGASIQACDEGGLHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPLHEAASKGKVDVCLALL 143
                                    |:::.|.....:|.|.   :..||||.||..|.|::.:.:|
plant    54 ------------------------AKIIELRPSLLSSRNA---YGDTPLHLAALLGDVNIVMQML 91

  Fly   144 QHGAN-HTIRNSEQKTPLELA-----DEATRPVL--TGEYRKDELLEAARSGAE-------DRL- 192
            ..|.. ::.||::.:|||.||     .||.:.::  |.....|||..|..||:.       :|. 
plant    92 DTGLELYSARNNKNQTPLHLAFVSIFMEAAKFIVEKTNSVDLDELNFALSSGSTCIVGIILERFP 156

  Fly   193 -LALLTPLNVNCHASDGRRSTPLHLAAGYNRIGIVEILLA-NGADVHAKDKGGLVPLHNACSYGH 255
             ||......|    .||.|||.||.|.....:.:..|||. |.....|.:..||.|||       
plant   157 ELARKNAWEV----EDGSRSTLLHYACDKGDLELTSILLGLNQGLEEALNSKGLSPLH------- 210

  Fly   256 FDVTKLLIQAGANVNANDLWAFTPLHEAASKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAPTRE 320
                 |.:|.|:.:         .|.|...||.:..|.                     ..|::|
plant   211 -----LAVQRGSVI---------ILEEFMDKSPLSFCV---------------------RTPSKE 240

  Fly   321 LRERIAFEYKGHCLLDACRKCDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLM--E 383
                                                        |..|||..:.:......|  .
plant   241 --------------------------------------------TVFHLAARNKNTDAFVFMAEN 261

  Fly   384 LLTRKGSLLNEKNKAFLTPLHLAAE------LLHYDAMEVLLKQGAKVNALDSLGQTPLHRCARD 442
            |.|....||.:|::...|.||:||.      |:.|    ::.|:...:...:::|....|...|.
plant   262 LGTSSPILLKKKDQQGNTVLHIAASVSCGSPLIRY----IVGKKIIDIRDRNNMGYRAYHLLPRQ 322

  Fly   443 EQAVRLLLSY-AADTNIVSLEGLTAAQLASDSVLKLLKNPPDSETHLLEAAKAGDLDTVRRIVLN 506
            .|....:.|| ..||.       |:.::.|       |....:|.|:      |..:.:|.:.| 
plant   323 AQDYEFISSYLRCDTK-------TSEEVDS-------KKAERNEPHI------GHSEVIRLLKL- 366

  Fly   507 NPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNA 560
              |.::..::..|..:..|.....::      .|||...:.|        |.||
plant   367 --IEISTSEIAERKKSKKHHVKRGHK------SLEHEMHIEA--------LQNA 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125 29/114 (25%)
ANK repeat 59..87 CDD:293786 9/27 (33%)
Ank_2 61..153 CDD:289560 22/92 (24%)
ANK repeat 89..120 CDD:293786 4/30 (13%)
ANK repeat 122..153 CDD:293786 10/31 (32%)
ANK 202..316 CDD:238125 26/114 (23%)
ANK repeat 212..240 CDD:293786 9/28 (32%)
Ank_2 214..306 CDD:289560 21/92 (23%)
ANK repeat 242..273 CDD:293786 8/30 (27%)
ANK repeat 275..306 CDD:293786 5/30 (17%)
ANK 361..478 CDD:238125 28/125 (22%)
ANK repeat 363..396 CDD:293786 9/34 (26%)
Ank_2 367..459 CDD:289560 25/100 (25%)
ANK 393..573 CDD:238125 35/175 (20%)
ANK repeat 398..429 CDD:293786 8/36 (22%)
ANK repeat 431..459 CDD:293786 8/28 (29%)
ANK repeat 483..515 CDD:293786 6/31 (19%)
Ank_4 486..540 CDD:290365 7/53 (13%)
ANK 512..637 CDD:238125 9/49 (18%)
ANK repeat 522..550 CDD:293786 5/27 (19%)
Ank_2 524..616 CDD:289560 8/37 (22%)
ANK repeat 552..583 CDD:293786 3/9 (33%)
ANK repeat 585..610 CDD:293786
ANK repeat 638..668 CDD:293786
Ank_4 641..693 CDD:290365
ANK 665..779 CDD:238125
ANK repeat 672..703 CDD:293786
Ank_2 677..769 CDD:289560
ANK repeat 705..736 CDD:293786
ANK repeat 738..769 CDD:293786
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
AT2G24600NP_001189592.1 ANK repeat 38..68 CDD:293786 12/58 (21%)
Ank_2 41..133 CDD:289560 32/123 (26%)
ANK 66..222 CDD:238125 53/183 (29%)
ANK repeat 70..102 CDD:293786 10/31 (32%)
Ank_4 171..222 CDD:290365 19/71 (27%)
ANK 173..285 CDD:238125 37/197 (19%)
ANK repeat 205..236 CDD:293786 13/72 (18%)
Ank_2 209..309 CDD:289560 30/189 (16%)
ANK repeat 238..274 CDD:293786 10/79 (13%)
PGG 399..506 CDD:290670 4/14 (29%)
PotE <406..>545 CDD:223605
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8400
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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