DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnks and asb11

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_999957.1 Gene:asb11 / 791758 ZFINID:ZDB-GENE-070112-532 Length:293 Species:Danio rerio


Alignment Length:277 Identity:89/277 - (32%)
Similarity:119/277 - (42%) Gaps:56/277 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   522 TPLHFAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWK 586
            ||||.||...|:..::.||..|..|..|...|:..||.||..||:...:||::|||:.|......
Zfish    39 TPLHDAALQGRLLPLRRLLSQGYNVGMATLDGITALHEACVGGHFTCAKLLLEHGADANAVTFDG 103

  Fly   587 FTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGN 651
            .|||..|...|...:..|:|.|                   .|.|..|.||..|  |.:|||:|:
Zfish   104 ATPLFSACCSGNPALVSLILTH-------------------SSAHHPAHLLCSP--LHEAAKRGH 147

  Fly   652 LARVQRLVTPESINCRDAQGRNSTPLHLAAGYNNFECAEYLLENGADVNAQDKGGLIPLHNASSY 716
            .|.|:.|:: ..:|.........|.|:.|....:.:|...||..||||.. .:|           
Zfish   148 TACVELLLS-HGVNVDMELPSVGTALYCACEVKSTDCVLTLLILGADVQC-GRG----------- 199

  Fly   717 GHLDIAALLIKHKTVVNATDKWGFTPLHEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELATA 781
              ||                    ||||.|.:.|..:...|||.||||...:|.||:||::|.:.
Zfish   200 --LD--------------------TPLHAACRVGGAKEAELLLEHGADRTSRNSEGKTPLDLTSD 242

  Fly   782 DDVKCLLQDAMATSLSQ 798
            ..:|.|||.|...||||
Zfish   243 QSIKHLLQTAGTCSLSQ 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125
ANK repeat 212..240 CDD:293786
Ank_2 214..306 CDD:289560
ANK repeat 242..273 CDD:293786
ANK repeat 275..306 CDD:293786
ANK 361..478 CDD:238125
ANK repeat 363..396 CDD:293786
Ank_2 367..459 CDD:289560
ANK 393..573 CDD:238125 20/50 (40%)
ANK repeat 398..429 CDD:293786
ANK repeat 431..459 CDD:293786
ANK repeat 483..515 CDD:293786
Ank_4 486..540 CDD:290365 7/17 (41%)
ANK 512..637 CDD:238125 36/114 (32%)
ANK repeat 522..550 CDD:293786 11/27 (41%)
Ank_2 524..616 CDD:289560 31/91 (34%)
ANK repeat 552..583 CDD:293786 13/30 (43%)
ANK repeat 585..610 CDD:293786 8/24 (33%)
ANK repeat 638..668 CDD:293786 10/29 (34%)
Ank_4 641..693 CDD:290365 13/51 (25%)
ANK 665..779 CDD:238125 32/113 (28%)
ANK repeat 672..703 CDD:293786 10/30 (33%)
Ank_2 677..769 CDD:289560 25/91 (27%)
ANK repeat 705..736 CDD:293786 3/30 (10%)
ANK repeat 738..769 CDD:293786 13/30 (43%)
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
asb11NP_999957.1 ANK 36..155 CDD:238125 46/136 (34%)
Ank_2 <36..99 CDD:289560 25/59 (42%)
ANK repeat 36..67 CDD:293786 11/27 (41%)
ANK repeat 69..100 CDD:293786 13/30 (43%)
Ank_2 74..164 CDD:289560 35/111 (32%)
ANK repeat 136..165 CDD:293786 10/31 (32%)
Ank_2 139..230 CDD:289560 35/125 (28%)
ANK repeat 167..197 CDD:293786 10/30 (33%)
ANK repeat 199..230 CDD:293786 16/63 (25%)
SOCS_ASB_like 255..293 CDD:239686 4/5 (80%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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