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Protein Alignment Tnks and Ankrd55

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_084174.2	Gene:	Ankrd55 / 77318	MGIID:	1924568	Length:	626	Species:	Mus musculus

Alignment Length:	864	Identity:	165/864 - (19%)
Similarity:	254/864 - (29%)	Gaps:	355/864 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 IQACDEGGLHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPLHEAASKGKVDVCLALLQHGA 147
            ::.||..|..||.:..|....:.|:||||.||:.||.|.:..|.|..|...|.::.|::||::||
Mouse    53 LECCDSEGCTPLMHAVSGRQVDTVKLLLKMGANINTQDAYGRTSLCLATYLGWLEGCVSLLRNGA 117

  Fly   148 NHTIRNSEQKTPLELADEATRPVLTGEYRKDELLEAARSGAEDRLLALLTPLNVNCHASDGRRST 212
            .|.|
Mouse   118 KHNI------------------------------------------------------------- 121

  Fly   213 PLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAG--ANVNANDLW 275
                                      .||.|.:|||.|.:.....:..:|:|..  :.:|..|..
Mouse   122 --------------------------PDKNGRLPLHAATAEPDVRLLIVLLQQSSLSEINHQDTE 160

  Fly   276 AFTPLHEAASKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAPTRELRERIAFEYKGHCLLDACRK 340
            ..||||.||..:|.:...:||.:||||||::...|:|:..|
Mouse   161 GMTPLHWAAFHNRPQHTQMLLKKGADPTLVDKDFKTALHWA------------------------ 201

  Fly   341 CDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLMELLTRKGSLLNEKNKAFLTPLHL 405
              |....:::|:.|::.                             |:|
Mouse   202 --VQSGNRILCSIILSH-----------------------------RQG---------------- 219

  Fly   406 AAELLHYDAMEVLLKQGAKVNALDSLGQTPLHRCARDEQAVRLLLSYAADTNIVSLEGLTAAQLA 470
             ..:::||               |..|:|.:|                          :.||...
Mouse   220 -PSIINYD---------------DESGKTCVH--------------------------IAAASGF 242

  Fly   471 SDSVLKLLKNPPDSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPV 535
            .|.:..|.|.|                            ..|.:.||....||||:||...:...
Mouse   243 GDIINDLAKVP----------------------------ECNLQALDVDDRTPLHWAAASGKAEC 279

  Fly   536 VQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDL-----------WKFTP 589
            ||.||:.|.:....|.....||..|...||.....||.:.|.......|           .:|:.
Mouse   280 VQSLLDLGMDSNLRDINESTPLAYALYCGHTACVRLLSREGRAEPARPLPSQNSQPQKKEGRFSM 344

  Fly   590 LHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGNLAR 654
            |::...|.|        |......:|::..|.|.:   |...:|.:::....:::|.
Mouse   345 LNQIFCKNK--------KEEQKAHQKDQSRARPKE---EETSEVNDIIATFDSVVDT-------- 390

  Fly   655 VQRLVTPESINCRDAQGRNSTPLHLAA-GYNNFECAEYLLENGADVNAQDKGGLIPLHNAS---- 714
                      ||   ||:....:.:.. .....|.::|||   .:..:..:.||.|:...|
Mouse   391 ----------NC---QGQPGDQVDMVVFKKRTSENSKYLL---PEKKSLARKGLPPIRTQSLPPI 439

  Fly   715 -SYGHLDIAALLIKHKTVVNATDKWGFTPLHEA--AQKGRTQLCSLLLAHGADAYMKNQ-EGQTP 775
             ..||...|:........:||      .|.|.|  :||.|::...|....|....::|. :|.|
Mouse   440 TLGGHFLTASQGAVSHAGLNA------GPQHTAQRSQKSRSEQDLLNNRTGCPVSLENPWKGDT- 497

  Fly   776 IELATADDVKCLLQDAMATSLSQQALSASTQSLTSSSPAPDATAAAAPG-------------TSS 827
                                  :|..|....:::||....|...|..||             .:.
Mouse   498 ----------------------RQVFSCKAWTVSSSDKLLDRLFAGQPGHQELSGPPHLPHLHNP 540

  Fly   828 SSSSAI--LSPT---------TETVLLPTGASMILS------------VPV-----PLPLSSSTR 864
            ||..|:  |||.         |...|.|......||            :|.     |.|...|.|
Mouse   541 SSGQALQHLSPNRPKIRDLPFTRNSLAPLPDQKFLSGEPLRTNRVLPAIPSQRGHDPSPAGESQR 605

  Fly   865 ISPAQGAEANGAEGSSSDD 883
            ......||.:|...|.:.|
Mouse   606 GHDPPRAEESGGSSSPTHD 624

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.