DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tnks and Ankrd65

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_001102897.1 Gene:Ankrd65 / 680734 RGDID:1588232 Length:365 Species:Rattus norvegicus


Alignment Length:468 Identity:128/468 - (27%)
Similarity:181/468 - (38%) Gaps:130/468 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   156 QKTPLELADEATRPVLTGEYRKDELLEAARSGAEDRLLALLTPLNVNCHASDGRRSTPLHLAAGY 220
            ::||   ||:..||:....:  ..|.:|...||...::.||.. ..:....|....||||||...
  Rat    18 EETP---ADKTDRPLTPQGW--STLFQAVWWGAPSLVMQLLRQ-GASVEERDHTGRTPLHLAVMR 76

  Fly   221 NRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAGANVNAN-DLWAFTPLHEAA 284
            ....:|.:||..||...|.|..|..|||.|..:||.:|.:||::.||:..|. .....||||.||
  Rat    77 GHAPLVRLLLQRGALAGAVDHTGRTPLHEAAWHGHSNVAELLLRRGASAAAPCSQTGLTPLHGAA 141

  Fly   285 SKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAP-TRELRERIAFEYKGHCLLDACRKCDVSRAKK 348
            :..|.             .|:.|.: :|.|:.| .:::|...|..:...|               
  Rat   142 ALGRT-------------LLVTCFT-AAPDSVPDVKDIRGWTATHWAAAC--------------- 177

  Fly   349 LVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLMELLTRKGSLLNEKNKAFLTPLHLAAELLHYD 413
                          |..|              ::||||..||:  :.:.|.|    ::|......
  Rat   178 --------------GQLP--------------VLELLTAGGSV--DLDGALL----VSAVAGSAS 208

  Fly   414 AMEVLLKQGAKVNALDSLGQTPLHRCA--RDEQAVRLLLSYAADTNIVSLEGLTAAQLASDSVLK 476
            |:.:||..||||:||||.|.|.|...|  ...|.:.:||.:.||.||                  
  Rat   209 ALRLLLTLGAKVDALDSTGATALGLAAGLGHHQEIEVLLGHGADPNI------------------ 255

  Fly   477 LLKNPPDSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLE 541
                                                 ||.:.|  :.||.||....:..:|.|:.
  Rat   256 -------------------------------------RDRNNR--SALHRAASGGCLRAIQLLVA 281

  Fly   542 HGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWKFTPLHEAAAKGKYDICKLLL 606
            .|.:|.|.|..||.|||.|...||.||...|:..||:|:.:.....||||.|...|...|.:|||
  Rat   282 KGTDVDARDSLGLTPLHYAARGGHREVVSHLLDRGAHVDAAGWLHKTPLHLAVECGHTTILELLL 346

  Fly   607 KHGADPMKKNRDG 619
            ..||:|..:.:.|
  Rat   347 SRGANPSLRTQWG 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125 2/6 (33%)
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125 38/114 (33%)
ANK repeat 212..240 CDD:293786 12/27 (44%)
Ank_2 214..306 CDD:289560 32/92 (35%)
ANK repeat 242..273 CDD:293786 13/31 (42%)
ANK repeat 275..306 CDD:293786 8/30 (27%)
ANK 361..478 CDD:238125 33/118 (28%)
ANK repeat 363..396 CDD:293786 8/32 (25%)
Ank_2 367..459 CDD:289560 30/93 (32%)
ANK 393..573 CDD:238125 48/181 (27%)
ANK repeat 398..429 CDD:293786 11/30 (37%)
ANK repeat 431..459 CDD:293786 10/29 (34%)
ANK repeat 483..515 CDD:293786 0/31 (0%)
Ank_4 486..540 CDD:290365 8/53 (15%)
ANK 512..637 CDD:238125 41/108 (38%)
ANK repeat 522..550 CDD:293786 9/27 (33%)
Ank_2 524..616 CDD:289560 37/91 (41%)
ANK repeat 552..583 CDD:293786 14/30 (47%)
ANK repeat 585..610 CDD:293786 10/24 (42%)
ANK repeat 638..668 CDD:293786
Ank_4 641..693 CDD:290365
ANK 665..779 CDD:238125
ANK repeat 672..703 CDD:293786
Ank_2 677..769 CDD:289560
ANK repeat 705..736 CDD:293786
ANK repeat 738..769 CDD:293786
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
Ankrd65NP_001102897.1 ANK 33..149 CDD:238125 40/131 (31%)
ANK repeat 33..63 CDD:293786 6/32 (19%)
Ank_2 37..123 CDD:289560 30/86 (35%)
ANK repeat 65..96 CDD:293786 12/30 (40%)
ANK repeat 98..123 CDD:293786 10/24 (42%)
ANK repeat 197..224 CDD:293786 11/30 (37%)
Ank_2 198..290 CDD:289560 36/152 (24%)
ANK 221..346 CDD:238125 50/181 (28%)
ANK repeat 227..257 CDD:293786 11/84 (13%)
ANK repeat 259..290 CDD:293786 10/32 (31%)
Ank_2 264..355 CDD:289560 37/90 (41%)
ANK repeat 292..323 CDD:293786 14/30 (47%)
ANK repeat 325..355 CDD:293786 13/29 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

Return to query results.
Submit another query.