| Sequence 1: | NP_001262963.1 | Gene: | Tnks / 43095 | FlyBaseID: | FBgn0027508 | Length: | 1520 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_065822.2 | Gene: | HACE1 / 57531 | HGNCID: | 21033 | Length: | 909 | Species: | Homo sapiens |
| Alignment Length: | 838 | Identity: | 181/838 - (21%) |
|---|---|---|---|
| Similarity: | 292/838 - (34%) | Gaps: | 207/838 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 481 PPDSET---HLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLEH 542
Fly 543 GAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWKFTPLHEAAAKGKYDICKLLLK 607
Fly 608 HGADPMKKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDAQGR 672
Fly 673 NSTPLHLAAGYNNFECAEYLLENGADVNAQDKGGLIPLHNASSYGHLDIAALLIKHKTVVNATDK 737
Fly 738 WGFTPLHEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELATADDVKCLLQDAMATSLSQQALS 802
Fly 803 ASTQSLTSSSPAPDATAAAAPGTSSSSSSAILSPTTETVLLPTGASMILSVPVPLPLSSSTRISP 867
Fly 868 AQGAEANGAEGSSSDDLLPDADTITNVSGFLSSQQLHHLI---------ELFERE----QITLDI 919
Fly 920 LAEMGHDD-------LKQVGVSAY-----GFRHKILKGIAQLRSTTG-----IGNNVNLCTLLVD 967
Fly 968 LL--------------PDDKEFVAVEEEM--------QATIREHRDNGQAGGYF--------TRY 1002
Fly 1003 -NIIRVQKVQNRKLWERYAHRRQEIAEENF----LQSNERMLFHGSPFIN-----------AIVQ 1051
Fly 1052 RGFDERHAYIGGMFGAGIYFAEHSSKSNQYV---YGI--GGGIGCPSHKDKSCYVCPRQLLLCRV 1111
Fly 1112 A---LGKSFLQYSAMKMAHAPPGHHSVVGRPSAGGLHFAEYVVYRGEQSY-PEYLITYQIVKPDD 1172
Fly 1173 SSS--------------GTEDTRXWMPSVGSTPTTTSPALHQPQTQQQPQQQQQQQPQ 1216 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Tnks | NP_001262963.1 | ANK | 49..163 | CDD:238125 | |
| ANK repeat | 59..87 | CDD:293786 | |||
| Ank_2 | 61..153 | CDD:289560 | |||
| ANK repeat | 89..120 | CDD:293786 | |||
| ANK repeat | 122..153 | CDD:293786 | |||
| ANK | 202..316 | CDD:238125 | |||
| ANK repeat | 212..240 | CDD:293786 | |||
| Ank_2 | 214..306 | CDD:289560 | |||
| ANK repeat | 242..273 | CDD:293786 | |||
| ANK repeat | 275..306 | CDD:293786 | |||
| ANK | 361..478 | CDD:238125 | |||
| ANK repeat | 363..396 | CDD:293786 | |||
| Ank_2 | 367..459 | CDD:289560 | |||
| ANK | 393..573 | CDD:238125 | 21/94 (22%) | ||
| ANK repeat | 398..429 | CDD:293786 | |||
| ANK repeat | 431..459 | CDD:293786 | |||
| ANK repeat | 483..515 | CDD:293786 | 9/34 (26%) | ||
| Ank_4 | 486..540 | CDD:290365 | 10/56 (18%) | ||
| ANK | 512..637 | CDD:238125 | 35/124 (28%) | ||
| ANK repeat | 522..550 | CDD:293786 | 3/27 (11%) | ||
| Ank_2 | 524..616 | CDD:289560 | 29/91 (32%) | ||
| ANK repeat | 552..583 | CDD:293786 | 13/30 (43%) | ||
| ANK repeat | 585..610 | CDD:293786 | 9/24 (38%) | ||
| ANK repeat | 638..668 | CDD:293786 | 5/29 (17%) | ||
| Ank_4 | 641..693 | CDD:290365 | 11/51 (22%) | ||
| ANK | 665..779 | CDD:238125 | 35/113 (31%) | ||
| ANK repeat | 672..703 | CDD:293786 | 10/30 (33%) | ||
| Ank_2 | 677..769 | CDD:289560 | 28/91 (31%) | ||
| ANK repeat | 705..736 | CDD:293786 | 9/30 (30%) | ||
| ANK repeat | 738..769 | CDD:293786 | 8/30 (27%) | ||
| SAM_tankyrase1,2 | 887..952 | CDD:188923 | 15/89 (17%) | ||
| SAM | 890..952 | CDD:197735 | 15/86 (17%) | ||
| tankyrase_like | 948..1170 | CDD:238718 | 50/281 (18%) | ||
| PARP | 961..1165 | CDD:279038 | 47/258 (18%) | ||
| HACE1 | NP_065822.2 | Ank_2 | <27..>283 | CDD:330894 | 85/317 (27%) |
| ANK 1 | 64..93 | 14/47 (30%) | |||
| ANK repeat | 66..95 | CDD:293786 | 13/30 (43%) | ||
| ANK | 92..217 | CDD:238125 | 44/145 (30%) | ||
| ANK repeat | 97..128 | CDD:293786 | 11/30 (37%) | ||
| ANK 2 | 97..126 | 11/28 (39%) | |||
| ANK repeat | 130..161 | CDD:293786 | 9/49 (18%) | ||
| ANK 3 | 130..159 | 9/47 (19%) | |||
| ANK repeat | 163..194 | CDD:293786 | 11/32 (34%) | ||
| ANK 4 | 163..192 | 10/30 (33%) | |||
| ANK 5 | 196..226 | 9/30 (30%) | |||
| ANK repeat | 196..221 | CDD:293786 | 9/25 (36%) | ||
| ANK 6 | 228..257 | 8/34 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 398..433 | 5/34 (15%) | |||
| HECTc | 554..903 | CDD:238033 | 42/214 (20%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4177 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||