DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tnks and ankrd31

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_001017911.1	Gene:	ankrd31 / 550610	ZFINID:	ZDB-GENE-050417-473	Length:	261	Species:	Danio rerio

Alignment Length:	146	Identity:	50/146 - (34%)
Similarity:	70/146 - (47%)	Gaps:	12/146 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   536 VQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWKFTPLHEAAAKGKYD 600
            |:.::..||.:..||..|..|||.|.:..:|::||:|:|.||..|.......|||.||.....|.
Zfish     8 VRDMISVGASINVADYAGWTPLHEAVNRNNYDITEVLLKAGAQANCKGDDGVTPLLEAIQYQYYK 72

  Fly   601 ICKLLLKHGADPMKKNRDGATPADLVKESDHD----VAELLRGPSALLDAAKKGNLARVQRLVTP 661
            |..||||:||||:.|...|.||.|::  :|..    |.:.|:...:  |.....|..|    .|.
Zfish    73 IVDLLLKYGADPLLKCDRGKTPMDMI--TDRSMCMVVEKYLQKTKS--DTFTADNSPR----TTD 129

  Fly   662 ESINCRDAQGRNSTPL 677
            ..:|....|.||..|:
Zfish   130 SGVNPSVDQSRNQNPI 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnks	NP_001262963.1	ANK	49..163	CDD:238125
		ANK repeat	59..87	CDD:293786
		Ank_2	61..153	CDD:289560
		ANK repeat	89..120	CDD:293786
		ANK repeat	122..153	CDD:293786
		ANK	202..316	CDD:238125
		ANK repeat	212..240	CDD:293786
		Ank_2	214..306	CDD:289560
		ANK repeat	242..273	CDD:293786
		ANK repeat	275..306	CDD:293786
		ANK	361..478	CDD:238125
		ANK repeat	363..396	CDD:293786
		Ank_2	367..459	CDD:289560
		ANK	393..573	CDD:238125	13/36 (36%)
		ANK repeat	398..429	CDD:293786
		ANK repeat	431..459	CDD:293786
		ANK repeat	483..515	CDD:293786
		Ank_4	486..540	CDD:290365	1/3 (33%)
		ANK	512..637	CDD:238125	40/104 (38%)
		ANK repeat	522..550	CDD:293786	3/13 (23%)
		Ank_2	524..616	CDD:289560	33/79 (42%)
		ANK repeat	552..583	CDD:293786	13/30 (43%)
		ANK repeat	585..610	CDD:293786	11/24 (46%)
		ANK repeat	638..668	CDD:293786	5/29 (17%)
		Ank_4	641..693	CDD:290365	9/37 (24%)
		ANK	665..779	CDD:238125	5/13 (38%)
		ANK repeat	672..703	CDD:293786	3/6 (50%)
		Ank_2	677..769	CDD:289560	0/1 (0%)
		ANK repeat	705..736	CDD:293786
		ANK repeat	738..769	CDD:293786
		SAM_tankyrase1,2	887..952	CDD:188923
		SAM	890..952	CDD:197735
		tankyrase_like	948..1170	CDD:238718
		PARP	961..1165	CDD:279038
ankrd31	NP_001017911.1	ANK	1..111	CDD:238125	40/104 (38%)
		Ank_2	1..87	CDD:289560	33/78 (42%)
		ANK repeat	24..55	CDD:293786	13/30 (43%)
		ANK repeat	57..82	CDD:293786	11/24 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910