DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnks and asb13a.1

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:XP_009298394.1 Gene:asb13a.1 / 436801 ZFINID:ZDB-GENE-040718-261 Length:311 Species:Danio rerio


Alignment Length:314 Identity:92/314 - (29%)
Similarity:142/314 - (45%) Gaps:55/314 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   212 TPLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAGANVNANDLWA 276
            ||:|.||...|...::.|:|.||.|:........|||:||...|.:..|:|::|||.|:...:..
Zfish    21 TPVHEAASLGRALQLQQLIAAGASVNIVSVDNFTPLHDACIQAHPNCVKILLEAGAQVDVRTIHG 85

  Fly   277 FTPLHEAASKSRVEVCSLLLSRGA--DPTLLNCHSKSAIDAAPTRELRERIAFEYKGHCLLDACR 339
            .|||..|.:...:|...||:..||  :|:|      :|:.|:|..|                ||.
Zfish    86 STPLCHACAAGSIESVKLLVDHGASVNPSL------TALTASPLHE----------------ACI 128

  Fly   340 KCDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLMELLTRKGSLLNEKNKAFLTPLH 404
            :.:..:    ||...|..:  |...:.:||...:||     .::|:..||:||...:..|.||||
Zfish   129 RGETCK----VCINTVFIL--YLFSSRVHLCAGNPD-----CVKLMIAKGALLEAFDIYFGTPLH 182

  Fly   405 LAAELLHYDAMEVLLKQGAKVNALDSLGQTPLHRCARDEQ--AVRLLLSYAADTNIVSLEGLTAA 467
            .|....|:|...:||..|||||| ....:|.||..||.|:  .|.||:.:..|.||         
Zfish   183 AACAKAHFDCALLLLNAGAKVNA-TKFHETALHHAARAEREDLVELLVEFGGDVNI--------- 237

  Fly   468 QLASDSVLKLLKN--PPDSETHLL---EAAKAGDLDTVRRIVLNNPISVNCRDL 516
               ||::..:.::  .|||.|:|.   ..:....|..:.||::...:.....:|
Zfish   238 ---SDNLDHIPRDYTKPDSPTNLCLLQYGSNPLSLQQLCRIIIRTMVGTRAMEL 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125 35/105 (33%)
ANK repeat 212..240 CDD:293786 11/27 (41%)
Ank_2 214..306 CDD:289560 32/93 (34%)
ANK repeat 242..273 CDD:293786 12/30 (40%)
ANK repeat 275..306 CDD:293786 11/32 (34%)
ANK 361..478 CDD:238125 40/118 (34%)
ANK repeat 363..396 CDD:293786 9/32 (28%)
Ank_2 367..459 CDD:289560 36/93 (39%)
ANK 393..573 CDD:238125 39/131 (30%)
ANK repeat 398..429 CDD:293786 16/30 (53%)
ANK repeat 431..459 CDD:293786 11/29 (38%)
ANK repeat 483..515 CDD:293786 7/34 (21%)
Ank_4 486..540 CDD:290365 6/34 (18%)
ANK 512..637 CDD:238125 1/5 (20%)
ANK repeat 522..550 CDD:293786
Ank_2 524..616 CDD:289560
ANK repeat 552..583 CDD:293786
ANK repeat 585..610 CDD:293786
ANK repeat 638..668 CDD:293786
Ank_4 641..693 CDD:290365
ANK 665..779 CDD:238125
ANK repeat 672..703 CDD:293786
Ank_2 677..769 CDD:289560
ANK repeat 705..736 CDD:293786
ANK repeat 738..769 CDD:293786
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
asb13a.1XP_009298394.1 ANK repeat 20..49 CDD:293786 11/27 (41%)
Ank_2 24..112 CDD:289560 30/87 (34%)
ANK 46..197 CDD:238125 50/183 (27%)
ANK repeat 51..82 CDD:293786 12/30 (40%)
ANK repeat 84..112 CDD:293786 9/27 (33%)
ANK 151..248 CDD:238125 39/114 (34%)
Ank_2 151..239 CDD:289560 37/105 (35%)
ANK repeat 176..206 CDD:293786 16/30 (53%)
ANK repeat 208..239 CDD:293786 12/42 (29%)
SOCS_ASB13 264..305 CDD:239699 4/25 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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