DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tnks and psmd10

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_991317.1 Gene:psmd10 / 403085 ZFINID:ZDB-GENE-050112-1 Length:226 Species:Danio rerio


Alignment Length:296 Identity:86/296 - (29%)
Similarity:119/296 - (40%) Gaps:89/296 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   484 SETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLEHGAEVYA 548
            |...:...|..|..:.:::.||::.......|.|.|  |.||:|.....|.:.||||:.|.||..
Zfish     6 SNVEVCNLAYGGKFEELKKCVLSDNSLAAKTDQDSR--TALHWACSAGHVNIAQFLLDLGVEVDL 68

  Fly   549 ADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWKFTPLHEAAAKGKYDICKLLLKHGADPM 613
            .|        :||                       |  ||||.||:.|:.:|.:.|:..||...
Zfish    69 KD--------DAC-----------------------W--TPLHIAASAGREEIVRSLISKGAQLN 100

  Fly   614 KKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDAQGRNSTPLH 678
            ..|::|.                                                      ||||
Zfish   101 SVNQNGC------------------------------------------------------TPLH 111

  Fly   679 LAAGYNNFECAEYLLENGADVNAQDKGGLIPLHNASSYGHLDIAALLIKHKTVVNATDKWGFTPL 743
            .||..|.:|.|:.|||||||.||.||....|||.||:.|:..:..||:|.....|..|..|.|||
Zfish   112 YAASKNLYEIAQILLENGADPNATDKLQSTPLHRASAKGNYRLIQLLLKESASTNIQDSEGNTPL 176

  Fly   744 HEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELA 779
            |.|..:.|.:...||:.|||..|::|:|..||:::|
Zfish   177 HLACDEERAEAAKLLVEHGASIYIENKEKMTPLQVA 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125
ANK repeat 212..240 CDD:293786
Ank_2 214..306 CDD:289560
ANK repeat 242..273 CDD:293786
ANK repeat 275..306 CDD:293786
ANK 361..478 CDD:238125
ANK repeat 363..396 CDD:293786
Ank_2 367..459 CDD:289560
ANK 393..573 CDD:238125 23/88 (26%)
ANK repeat 398..429 CDD:293786
ANK repeat 431..459 CDD:293786
ANK repeat 483..515 CDD:293786 5/30 (17%)
Ank_4 486..540 CDD:290365 14/53 (26%)
ANK 512..637 CDD:238125 32/124 (26%)
ANK repeat 522..550 CDD:293786 12/27 (44%)
Ank_2 524..616 CDD:289560 26/91 (29%)
ANK repeat 552..583 CDD:293786 2/30 (7%)
ANK repeat 585..610 CDD:293786 10/24 (42%)
ANK repeat 638..668 CDD:293786 0/29 (0%)
Ank_4 641..693 CDD:290365 9/51 (18%)
ANK 665..779 CDD:238125 48/113 (42%)
ANK repeat 672..703 CDD:293786 18/30 (60%)
Ank_2 677..769 CDD:289560 42/91 (46%)
ANK repeat 705..736 CDD:293786 10/30 (33%)
ANK repeat 738..769 CDD:293786 13/30 (43%)
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
psmd10NP_991317.1 Ank_4 13..60 CDD:290365 14/48 (29%)
ANK repeat 39..70 CDD:293786 14/32 (44%)
ANK 39..68 CDD:197603 14/30 (47%)
Ank_2 44..136 CDD:289560 46/178 (26%)
ANK 67..192 CDD:238125 56/211 (27%)
ANK repeat 72..103 CDD:293786 14/55 (25%)
ANK repeat 105..136 CDD:293786 19/84 (23%)
Ank_2 110..202 CDD:289560 42/91 (46%)
ANK repeat 138..169 CDD:293786 10/30 (33%)
ANK repeat 171..202 CDD:293786 13/30 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1759
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.940

Return to query results.
Submit another query.