DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnks and Asb7

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_001102385.1 Gene:Asb7 / 365277 RGDID:1305154 Length:318 Species:Rattus norvegicus


Alignment Length:326 Identity:94/326 - (28%)
Similarity:132/326 - (40%) Gaps:77/326 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   479 KNPP-DSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLEH 542
            :||. ..|..:..|..|||:.|||: :|....|.|.||.:|  .|.|||:|...:...|:..|||
  Rat     8 RNPELQEELQIQAAVAAGDVHTVRK-MLEQGYSPNGRDANG--WTLLHFSAARGKERCVRVFLEH 69

  Fly   543 GAEVYAADK-GGLVPLHNACSYGHYEVTELLVKHG-----ANVNVSDLWKFTPLHEAAAKGKYDI 601
            ||:....|. ||...||.|..:|...:..|:::..     .|...:|.|  ||||.||..|:...
  Rat    70 GADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGW--TPLHVAAHYGRDSF 132

  Fly   602 CKLLLKHGA--DPMKKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESI 664
            .:|||:..|  ||:...  |.||..|.         ::|..|:.:            |::...|.
  Rat   133 VRLLLEFKAEVDPLSDK--GTTPLQLA---------IIRERSSCV------------RILLDHSA 174

  Fly   665 NCRDAQGRNSTPLHLAAGYNNFECAEYLLENGADVNAQDKGGLIPLHNASSYGHLDIAALLIKHK 729
            |. |.|  |...|..|...:|.......|:.|||.|               .|.|:.        
  Rat   175 NI-DIQ--NGFLLRYAVIKSNHSYCRMFLQRGADTN---------------LGRLED-------- 213

  Fly   730 TVVNATDKWGFTPLHEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELA---TADDVKCL--LQ 789
                     |.||||.:|.:.......:|..:|||...:|.|||||:.::   :.....||  ||
  Rat   214 ---------GQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQ 269

  Fly   790 D 790
            |
  Rat   270 D 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125
ANK repeat 212..240 CDD:293786
Ank_2 214..306 CDD:289560
ANK repeat 242..273 CDD:293786
ANK repeat 275..306 CDD:293786
ANK 361..478 CDD:238125
ANK repeat 363..396 CDD:293786
Ank_2 367..459 CDD:289560
ANK 393..573 CDD:238125 35/95 (37%)
ANK repeat 398..429 CDD:293786
ANK repeat 431..459 CDD:293786
ANK repeat 483..515 CDD:293786 11/31 (35%)
Ank_4 486..540 CDD:290365 19/53 (36%)
ANK 512..637 CDD:238125 43/132 (33%)
ANK repeat 522..550 CDD:293786 11/27 (41%)
Ank_2 524..616 CDD:289560 34/99 (34%)
ANK repeat 552..583 CDD:293786 8/35 (23%)
ANK repeat 585..610 CDD:293786 11/24 (46%)
ANK repeat 638..668 CDD:293786 5/29 (17%)
Ank_4 641..693 CDD:290365 10/51 (20%)
ANK 665..779 CDD:238125 30/113 (27%)
ANK repeat 672..703 CDD:293786 9/30 (30%)
Ank_2 677..769 CDD:289560 20/91 (22%)
ANK repeat 705..736 CDD:293786 2/30 (7%)
ANK repeat 738..769 CDD:293786 10/30 (33%)
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
Asb7NP_001102385.1 PHA02875 21..>241 CDD:165206 80/282 (28%)
ANK repeat 46..77 CDD:293786 12/32 (38%)
ANK repeat 81..114 CDD:293786 7/32 (22%)
ANK repeat 116..147 CDD:293786 15/32 (47%)
ANK repeat 149..180 CDD:293786 11/56 (20%)
ANK repeat 213..244 CDD:293786 10/47 (21%)
PTZ00322 219..>272 CDD:140343 17/52 (33%)
SOCS_ASB7 273..317 CDD:239696
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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