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Protein Alignment Tnks and ANKRD42

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_001287904.1	Gene:	ANKRD42 / 338699	HGNCID:	26752	Length:	527	Species:	Homo sapiens

Alignment Length:	437	Identity:	116/437 - (26%)
Similarity:	174/437 - (39%)	Gaps:	73/437 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 KNKAFLTPLHLAAELLHYDAMEVLLKQGAKVNALDSLGQ-TPLHRCARDE--QAVRLLLSYAADT 456
            :.|.....:|.|........:..::.:||.:|.||.|.: ||||..|...  :.:..||.:.||.
Human    22 RKKVHFGSIHDAVRAGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADI 86

  Fly   457 NIVSLEGLTAAQLASDSVLKLLKNPPDSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHS 521
            ..|:..|.||:.:                     ||..|....|:.:::|   ..|....|.|..
Human    87 THVTTRGWTASHI---------------------AAIRGQDACVQALIMN---GANLTAQDDRGC 127

  Fly   522 TPLHFAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLWK 586
            ||||.||.......:|.:|..|.:....||....|:|.|..:|.....:||||.|.::...|...
Human   128 TPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNG 192

  Fly   587 FTPLHEAAAKGKYDICKLLLKH--GADPMKK--NRDGATPADLVKE-----------------SD 630
            ..|:|.||.:|.....|.|:..  .|..:.|  |.:|....||.:.                 .|
Human   193 NLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKD 257

  Fly   631 HDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDAQGRNSTPLHLAAGYNNFECAEYLLEN 695
            .:..|.|..|..:  ||.||:|..:::||....||..:.....|||:|.|||..:.||.::|::.
Human   258 LEDQETLAFPGHV--AAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKM 320

  Fly   696 GADVNAQDKGGLIPLHNASSYGHLDIAALL-------IKHKTVVNATD-KWGFTPLHEAAQKGRT 752
            |||.|..:|.|..|...|..:.||....||       |..:..::..| |:......|.:...:.
Human   321 GADSNITNKAGERPSDVAKRFAHLAAVKLLEELQKYDIDDENEIDENDVKYFIRHGVEGSTDAKD 385

  Fly   753 QLCSLLLAHGAD----AYMKNQEGQTPIELA----------TADDVK 785
            .|| |......|    ||.|..|.:..:|:|          |.:|:|
Human   386 DLC-LSDLDKTDARMRAYKKIVELRHLLEIAESNYKHLGGITEEDLK 431

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.