DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tnks and CG44001

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_001033874.2	Gene:	CG44001 / 326173	FlyBaseID:	FBgn0264743	Length:	181	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	59/187 - (31%)
Similarity:	87/187 - (46%)	Gaps:	15/187 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   608 HGADPMKKNRDGATPADLVKESDHDVAELLRGPSALLDAAKKGNLARVQRLVTPESINCRDAQGR 672
            |.||..|.::........:.:.|.|     ||   :.:||....:.||:..:.......||  ..
  Fly     4 HSADNCKCHKQTQPAQQTLSDMDFD-----RG---IWNAAIYNEVERVREFIKKGQSMARD--DC 58

  Fly   673 NSTPLHLAAGYNNFECAEYLLENG-ADVNAQDKGGLIPLHNASSYGHLDIAALLIKHKTVVNATD 736
            :.|.||.||...|....:.||:.| |||||..|.|...||.|:..|||:|..||::||..:...|
  Fly    59 DYTALHYAARNGNEPICKLLLDEGKADVNAVTKAGATALHRAAMMGHLEIVKLLVEHKANLLLQD 123

  Fly   737 KWGFTPLHEAAQKGRTQLCSLLLAHGAD-AYMKNQEGQTPIELA---TADDVKCLLQ 789
            :.|.|.||.|..:|..::|.:|||.... ..:|:::.:...|..   ..||.|.||:
  Fly   124 ESGQTALHRAVMRGHLEVCRILLAKEPTLKLVKDKKDKIAFEYIMENANDDFKLLLK 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnks	NP_001262963.1	ANK	49..163	CDD:238125
		ANK repeat	59..87	CDD:293786
		Ank_2	61..153	CDD:289560
		ANK repeat	89..120	CDD:293786
		ANK repeat	122..153	CDD:293786
		ANK	202..316	CDD:238125
		ANK repeat	212..240	CDD:293786
		Ank_2	214..306	CDD:289560
		ANK repeat	242..273	CDD:293786
		ANK repeat	275..306	CDD:293786
		ANK	361..478	CDD:238125
		ANK repeat	363..396	CDD:293786
		Ank_2	367..459	CDD:289560
		ANK	393..573	CDD:238125
		ANK repeat	398..429	CDD:293786
		ANK repeat	431..459	CDD:293786
		ANK repeat	483..515	CDD:293786
		Ank_4	486..540	CDD:290365
		ANK	512..637	CDD:238125	6/28 (21%)
		ANK repeat	522..550	CDD:293786
		Ank_2	524..616	CDD:289560	4/7 (57%)
		ANK repeat	552..583	CDD:293786
		ANK repeat	585..610	CDD:293786	1/1 (100%)
		ANK repeat	638..668	CDD:293786	6/29 (21%)
		Ank_4	641..693	CDD:290365	12/51 (24%)
		ANK	665..779	CDD:238125	42/115 (37%)
		ANK repeat	672..703	CDD:293786	14/31 (45%)
		Ank_2	677..769	CDD:289560	37/93 (40%)
		ANK repeat	705..736	CDD:293786	12/30 (40%)
		ANK repeat	738..769	CDD:293786	10/31 (32%)
		SAM_tankyrase1,2	887..952	CDD:188923
		SAM	890..952	CDD:197735
		tankyrase_like	948..1170	CDD:238718
		PARP	961..1165	CDD:279038
CG44001	NP_001033874.2	Ank_4	31..79	CDD:290365	12/49 (24%)
		ANK	54..>148	CDD:238125	39/95 (41%)
		ANK repeat	61..90	CDD:293786	14/28 (50%)
		Ank_2	63..149	CDD:289560	37/85 (44%)
		ANK repeat	92..123	CDD:293786	12/30 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24180
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100