DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnks and Ankrd65

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:NP_001357751.1 Gene:Ankrd65 / 242805 MGIID:2685285 Length:364 Species:Mus musculus


Alignment Length:403 Identity:124/403 - (30%)
Similarity:158/403 - (39%) Gaps:96/403 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 LFEACKTGEIAKVKKLITP-QTVNARDTAGRKSTPLHFAAGYGRREVVEFLLNSGASIQACDEGG 90
            ||:|...|..:.|.:|:.. .:|..||..||  ||||.|...|...:|..||..||...|.|..|
Mouse    37 LFQAVWWGAPSLVMQLLRQGSSVEERDHTGR--TPLHLAVMRGHAPLVRLLLQRGALAGAPDHTG 99

  Fly    91 LHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPLHEAASKGKV-----------------DV 138
            ..|||.....||:.|..|||:.|||.........||||.||:.|:.                 ||
Mouse   100 RTPLHEAAWHGHSNVAELLLRRGASAAACSQTGLTPLHGAAALGRTLLVTSFTVASDSGSDVKDV 164

  Fly   139 CLALLQHG--ANHTIRNSEQKTPLELADEATRPVLTGEYRKDELLEAARSGAEDRLLALLTPLNV 201
                  .|  |.|......|...|||........|.|     .||.:|.:|:...|..||| |..
Mouse   165 ------RGWTAAHWAAACGQLAVLELLSAGGNADLDG-----ALLVSAIAGSTSSLQLLLT-LGA 217

  Fly   202 NCHASDGRRSTPLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFDVTKLLIQAG 266
            .....|...:|.|.||||......:|:||.:|||.:.:|:.....||.|.:.||..||:||:..|
Mouse   218 KVDTQDSTGATALGLAAGLGHHQDIEVLLDHGADPNIRDRNNRSALHRAATGGHLRVTQLLVAKG 282

  Fly   267 ANVNANDLWAFTPLHEAASKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAPTRELRERIAFEYKG 331
            ..::|.|....||||.||....|||.|.||.|||.           |:||               
Mouse   283 IEIDAQDSLGLTPLHHAARGGHVEVVSHLLDRGAH-----------INAA--------------- 321

  Fly   332 HCLLDACRKCDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLMELLTRKGSLLNEKN 396
                                    .::|    .|||||||   :......:|||..:|:     |
Mouse   322 ------------------------GWLH----KTPLHLAV---ENGHSTTVELLLSRGA-----N 350

  Fly   397 KAFLTPLHLAAEL 409
            ....|....||::
Mouse   351 STLRTQWGEAAQI 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125 45/132 (34%)
ANK repeat 59..87 CDD:293786 12/27 (44%)
Ank_2 61..153 CDD:289560 36/110 (33%)
ANK repeat 89..120 CDD:293786 13/30 (43%)
ANK repeat 122..153 CDD:293786 12/49 (24%)
ANK 202..316 CDD:238125 42/113 (37%)
ANK repeat 212..240 CDD:293786 12/27 (44%)
Ank_2 214..306 CDD:289560 39/91 (43%)
ANK repeat 242..273 CDD:293786 11/30 (37%)
ANK repeat 275..306 CDD:293786 15/30 (50%)
ANK 361..478 CDD:238125 15/49 (31%)
ANK repeat 363..396 CDD:293786 11/32 (34%)
Ank_2 367..459 CDD:289560 13/43 (30%)
ANK 393..573 CDD:238125 4/17 (24%)
ANK repeat 398..429 CDD:293786 3/12 (25%)
ANK repeat 431..459 CDD:293786
ANK repeat 483..515 CDD:293786
Ank_4 486..540 CDD:290365
ANK 512..637 CDD:238125
ANK repeat 522..550 CDD:293786
Ank_2 524..616 CDD:289560
ANK repeat 552..583 CDD:293786
ANK repeat 585..610 CDD:293786
ANK repeat 638..668 CDD:293786
Ank_4 641..693 CDD:290365
ANK 665..779 CDD:238125
ANK repeat 672..703 CDD:293786
Ank_2 677..769 CDD:289560
ANK repeat 705..736 CDD:293786
ANK repeat 738..769 CDD:293786
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
Ankrd65NP_001357751.1 ANK repeat 33..63 CDD:293786 7/25 (28%)
PHA03095 49..>347 CDD:222980 115/368 (31%)
ANK repeat 65..96 CDD:293786 14/32 (44%)
ANK repeat 98..123 CDD:293786 10/24 (42%)
ANK repeat 165..223 CDD:293786 18/63 (29%)
ANK repeat 226..256 CDD:293786 12/29 (41%)
ANK repeat 258..289 CDD:293786 11/30 (37%)
ANK repeat 291..320 CDD:293786 16/39 (41%)
ANK repeat 324..354 CDD:293786 13/41 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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