DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tnks and LOC101735265

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	XP_031760086.1	Gene:	LOC101735265 / 101735265	-ID:	-	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	49/264 - (18%)
Similarity:	80/264 - (30%)	Gaps:	114/264 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   872 EANGAEGSSSDDLLPDADTITNVSGFLSSQQLHHLIELFEREQITLDILAEMGHDDLKQVGVSAY 936
            |.:...|:...|.|..:|.    |||:       ..:..|...:...:||.:....|:.....
Frog    30 ETDSESGTRDGDCLTSSDG----SGFI-------CYKCGETFTVNSHLLAHLCGTQLRSYSGE-- 81

  Fly   937 GFRHKILKGIAQLRSTTGIGNNVNLCTLLVD---LLPDDKEFVAVEEEMQATIREHRDNGQAGGY 998
                       :|.|.|..|...:|...||.   :...:|.|..:|               .|..
Frog    82 -----------KLYSCTECGKRFSLFPSLVTHIRIHAGEKPFTCIE---------------CGKT 120

  Fly   999 FTRYNIIRVQKVQNRKLWERYAHRRQE-----IAEENFLQSNERMLFHGSPFINAIVQRGFDERH 1058
            |.|.:.:|:    ::||     ||.|:     |..|.|:  :||.|                :.|
Frog   121 FNRKDHLRM----HQKL-----HREQKQFTCAICAERFV--SERKL----------------QTH 158

  Fly  1059 AYIGGMFGAGIYFAEHSSKSNQYVYGIGGGIGCPSHKDKSCYVCPRQLLLCRVALGKSFLQYSAM 1123
            ..|                                |.:|:.:.|..    |    ||||.:.|::
Frog   159 QAI--------------------------------HMEKNLFTCTE----C----GKSFSKKSSL 183

  Fly  1124 KMAH 1127
            ::.|
Frog   184 RVHH 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnks	NP_001262963.1	ANK	49..163	CDD:238125
		ANK repeat	59..87	CDD:293786
		Ank_2	61..153	CDD:289560
		ANK repeat	89..120	CDD:293786
		ANK repeat	122..153	CDD:293786
		ANK	202..316	CDD:238125
		ANK repeat	212..240	CDD:293786
		Ank_2	214..306	CDD:289560
		ANK repeat	242..273	CDD:293786
		ANK repeat	275..306	CDD:293786
		ANK	361..478	CDD:238125
		ANK repeat	363..396	CDD:293786
		Ank_2	367..459	CDD:289560
		ANK	393..573	CDD:238125
		ANK repeat	398..429	CDD:293786
		ANK repeat	431..459	CDD:293786
		ANK repeat	483..515	CDD:293786
		Ank_4	486..540	CDD:290365
		ANK	512..637	CDD:238125
		ANK repeat	522..550	CDD:293786
		Ank_2	524..616	CDD:289560
		ANK repeat	552..583	CDD:293786
		ANK repeat	585..610	CDD:293786
		ANK repeat	638..668	CDD:293786
		Ank_4	641..693	CDD:290365
		ANK	665..779	CDD:238125
		ANK repeat	672..703	CDD:293786
		Ank_2	677..769	CDD:289560
		ANK repeat	705..736	CDD:293786
		ANK repeat	738..769	CDD:293786
		SAM_tankyrase1,2	887..952	CDD:188923	9/64 (14%)
		SAM	890..952	CDD:197735	8/61 (13%)
		tankyrase_like	948..1170	CDD:238718	37/188 (20%)
		PARP	961..1165	CDD:279038	33/175 (19%)
LOC101735265	XP_031760086.1	C2H2 Zn finger	53..78	CDD:275368	4/24 (17%)
		COG5048	82..466	CDD:227381	37/188 (20%)
		C2H2 Zn finger	86..106	CDD:275368	5/19 (26%)
		C2H2 Zn finger	114..134	CDD:275368	7/43 (16%)
		C2H2 Zn finger	143..162	CDD:275368	8/68 (12%)
		C2H2 Zn finger	170..190	CDD:275368	8/26 (31%)
		C2H2 Zn finger	198..218	CDD:275368
		C2H2 Zn finger	226..246	CDD:275368
		C2H2 Zn finger	253..273	CDD:275368
		C2H2 Zn finger	281..301	CDD:275368
		C2H2 Zn finger	309..329	CDD:275368
		C2H2 Zn finger	337..357	CDD:275368
		C2H2 Zn finger	365..385	CDD:275368
		C2H2 Zn finger	393..413	CDD:275368
		C2H2 Zn finger	421..441	CDD:275368
		C2H2 Zn finger	449..469	CDD:275368
		zf-H2C2_2	462..486	CDD:404364
		C2H2 Zn finger	477..497	CDD:275368
		SFP1	<499..582	CDD:227516
		C2H2 Zn finger	505..525	CDD:275368
		C2H2 Zn finger	533..553	CDD:275368
		C2H2 Zn finger	561..581	CDD:275368
		zf-H2C2_2	574..597	CDD:404364
		C2H2 Zn finger	589..609	CDD:275368
		zf-H2C2_2	602..626	CDD:404364
		C2H2 Zn finger	617..637	CDD:275368
		C2H2 Zn finger	645..665	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1115202at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010