DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tnks and LOC100498424

DIOPT Version :9

Sequence 1:	NP_001262963.1	Gene:	Tnks / 43095	FlyBaseID:	FBgn0027508	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	XP_002938439.1	Gene:	LOC100498424 / 100498424	-ID:	-	Length:	234	Species:	Xenopus tropicalis

Alignment Length:	167	Identity:	60/167 - (35%)
Similarity:	86/167 - (51%)	Gaps:	12/167 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   647 AKKGNLARVQRLVT---PESINCRDAQGRNSTPLHLAAGYNNFECAEYLLENGADVNAQDKGGLI 708
            |.:||:.:::.|::   .|.::.:|..|:  |||:.||........|.||..||:||:..|.|..
Frog    38 ASRGNVEKLRVLLSTTDKELVDRKDYYGK--TPLYWAAYKGQRLAMELLLHYGANVNSCCKHGGT 100

  Fly   709 PLHNASSYGHLDIAALLIKHKTVVNATDKWGFTPLHEAAQKGRTQLCSLLLAHGADAYMKNQE-G 772
            |||.|... ..|.|.|||:|...||..|.||.||::.||..|:|:...||:..|||...||:: |
Frog   101 PLHAAIGL-FPDCALLLIQHGADVNLQDNWGVTPMYLAACSGQTECIRLLVQAGADITYKNKKTG 164

  Fly   773 QTPIELAT-----ADDVKCLLQDAMATSLSQQALSAS 804
            ..|..||:     |....|..|......||:|.:.|:
Frog   165 LPPKRLASQVGFIAWIESCSRQPRSLKHLSRQRIRAT 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnks	NP_001262963.1	ANK	49..163	CDD:238125
		ANK repeat	59..87	CDD:293786
		Ank_2	61..153	CDD:289560
		ANK repeat	89..120	CDD:293786
		ANK repeat	122..153	CDD:293786
		ANK	202..316	CDD:238125
		ANK repeat	212..240	CDD:293786
		Ank_2	214..306	CDD:289560
		ANK repeat	242..273	CDD:293786
		ANK repeat	275..306	CDD:293786
		ANK	361..478	CDD:238125
		ANK repeat	363..396	CDD:293786
		Ank_2	367..459	CDD:289560
		ANK	393..573	CDD:238125
		ANK repeat	398..429	CDD:293786
		ANK repeat	431..459	CDD:293786
		ANK repeat	483..515	CDD:293786
		Ank_4	486..540	CDD:290365
		ANK	512..637	CDD:238125
		ANK repeat	522..550	CDD:293786
		Ank_2	524..616	CDD:289560
		ANK repeat	552..583	CDD:293786
		ANK repeat	585..610	CDD:293786
		ANK repeat	638..668	CDD:293786	5/23 (22%)
		Ank_4	641..693	CDD:290365	13/48 (27%)
		ANK	665..779	CDD:238125	46/114 (40%)
		ANK repeat	672..703	CDD:293786	12/30 (40%)
		Ank_2	677..769	CDD:289560	38/91 (42%)
		ANK repeat	705..736	CDD:293786	13/30 (43%)
		ANK repeat	738..769	CDD:293786	13/30 (43%)
		SAM_tankyrase1,2	887..952	CDD:188923
		SAM	890..952	CDD:197735
		tankyrase_like	948..1170	CDD:238718
		PARP	961..1165	CDD:279038
LOC100498424	XP_002938439.1	Ank_2	<28..93	CDD:372319	18/56 (32%)
		ANK repeat	31..62	CDD:293786	5/23 (22%)
		ANK repeat	64..95	CDD:293786	13/32 (41%)
		Ank_2	69..160	CDD:372319	38/91 (42%)
		ANK repeat	97..127	CDD:293786	13/30 (43%)
		ANK repeat	129..160	CDD:293786	13/30 (43%)
		SOCS_ASB_like	185..226	CDD:239686	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910