DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnks and ankrd55

DIOPT Version :9

Sequence 1:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster
Sequence 2:XP_001345419.4 Gene:ankrd55 / 100006755 ZFINID:ZDB-GENE-080104-7 Length:651 Species:Danio rerio


Alignment Length:882 Identity:172/882 - (19%)
Similarity:270/882 - (30%) Gaps:356/882 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 AAGYGRREVVEFLLNSGASI-QACDEGGLHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPL 127
            ||..|....:..::....|| :.||..|..||.:..|....:.|:||||.|||.||.|....|.|
Zfish    27 AAANGDVNTLTTVIREDPSILECCDGEGSTPLMHAVSGRQVDTVKLLLKMGASINTQDACGRTSL 91

  Fly   128 HEAASKGKVDVCLALLQHGANHTIRNSEQKTPLELADEATRPVLTGEYRKDELLEAARSGAEDRL 192
            ......|.::.|:.||::||...|.:...:.|                     :.||.:..:.||
Zfish    92 SLGTYLGWLEGCVCLLRNGAKQNIPDKNGRLP---------------------IHAATAETDFRL 135

  Fly   193 LALLTPLNVNCHASDGRRSTPLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNACSYGHFD 257
            :|:|...:..|                               :::.:|..|:..||.||.:..  
Zfish   136 MAVLLQQSTLC-------------------------------EINHQDNEGMTALHWACFHNR-- 167

  Fly   258 VTKLLIQAGANVNANDLWAFTPLHEAASKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAPTRELR 322
                                 |.|..|          ||.:||||||::...|:|:..|      
Zfish   168 ---------------------PEHSQA----------LLQKGADPTLVDKDFKTALHWA------ 195

  Fly   323 ERIAFEYKGHCLLDACRKCDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGKRKQLMELLTR 387
                                |....:|:|                                    
Zfish   196 --------------------VQSGSRLMC------------------------------------ 204

  Fly   388 KGSLLNEKNKAFLTPLHLAAELLHYDAMEVLLKQGAKVNALDSLGQTPLHRCARDEQAVRLLLSY 452
              ||:.|.|        |.:.:::||               |..|:|.:|               
Zfish   205 --SLILEHN--------LGSSVINYD---------------DENGKTCVH--------------- 229

  Fly   453 AADTNIVSLEGLTAAQLASDSVLKLLKNPPDSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLD 517
                       :.||...||.:.:|.:   .|||:|                       ...|:|
Zfish   230 -----------IAAAAGFSDIIYELSR---ISETNL-----------------------QALDVD 257

  Fly   518 GRHSTPLHFAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVS 582
            .|  ||||:||...:...||.|||.|.|....|.....||..|...||....:||    :..|.|
Zfish   258 ER--TPLHWAAAAGKDDCVQVLLELGVEPSPRDINENTPLTYAMYCGHTACIKLL----STENRS 316

  Fly   583 DLWKFTPLH------EAAAKGKYDICKLLLKHGADPMKKNRDGATPAD-----LVKESDHDVAEL 636
            :  ...|||      ....:||:    .:|.|.....||:.......|     .:||...:|.::
Zfish   317 E--SSRPLHAQNSDPSIRKEGKF----RMLNHIFSKKKKDLHPCQQTDSSQECQLKEETSEVDDI 375

  Fly   637 LRGPSALLDAA----------------KKGNLARVQRLVTPESINCRD------AQGRNSTPLHL 679
            :    .:.|..                |:.|.:....||  |..:|:|      .:.::..|:.|
Zfish   376 I----TMFDCVAEPFSRDESENSSTVRKRTNDSEKVHLV--EDTSCKDFPILPPIRTQSLPPITL 434

  Fly   680 AAGYNNFECAEYLLENGADVNAQDKGGLIPLH----------------------NASSYGHLDIA 722
                     .:.||.|  .:..:..||.:..|                      .|..:|....:
Zfish   435 ---------GKSLLVN--SLAHRTSGGHVVGHLAHRSQKSKSEHDLFDGKSKEQKAIGHGWKTES 488

  Fly   723 ALLIKHKTVVNATDKWGFTPLHEAAQKGRTQLCSLLLAHGADAYMKNQEGQTPIELATADDVKCL 787
            :.::.||.       |..||......|         |.|.:         .:|:::..::....:
Zfish   489 SHILTHKA-------WIATPSERLLDK---------LLHAS---------SSPLDVLCSNQTPYI 528

  Fly   788 LQDAMATSLSQQALSASTQSLTSSSPAPDATAA----------AAPGTSSSSSS-----AILSPT 837
            .::..|.......|.....:||.:|.||.....          .:.|...|.||     |:|.|.
Zfish   529 QRNDQAAQNHLLPLRVRESALTRNSLAPIRDHCTHRFSLPPDQVSQGVRKSKSSVGVGLAVLPPP 593

  Fly   838 TETVLLPTG---ASMILSVPVPL---PLSSSTRISPA 868
            ..:.|...|   :..:.|.|.||   || .:.::.||
Zfish   594 FASKLHRVGVPQSPSLGSFPTPLTGEPL-RNIQVLPA 629

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TnksNP_001262963.1 ANK 49..163 CDD:238125 32/99 (32%)
ANK repeat 59..87 CDD:293786 5/23 (22%)
Ank_2 61..153 CDD:289560 31/89 (35%)
ANK repeat 89..120 CDD:293786 14/30 (47%)
ANK repeat 122..153 CDD:293786 9/30 (30%)
ANK 202..316 CDD:238125 20/113 (18%)
ANK repeat 212..240 CDD:293786 0/27 (0%)
Ank_2 214..306 CDD:289560 17/91 (19%)
ANK repeat 242..273 CDD:293786 5/30 (17%)
ANK repeat 275..306 CDD:293786 11/30 (37%)
ANK 361..478 CDD:238125 15/116 (13%)
ANK repeat 363..396 CDD:293786 3/32 (9%)
Ank_2 367..459 CDD:289560 11/91 (12%)
ANK 393..573 CDD:238125 41/179 (23%)
ANK repeat 398..429 CDD:293786 3/30 (10%)
ANK repeat 431..459 CDD:293786 3/27 (11%)
ANK repeat 483..515 CDD:293786 4/31 (13%)
Ank_4 486..540 CDD:290365 13/53 (25%)
ANK 512..637 CDD:238125 39/135 (29%)
ANK repeat 522..550 CDD:293786 13/27 (48%)
Ank_2 524..616 CDD:289560 29/97 (30%)
ANK repeat 552..583 CDD:293786 8/30 (27%)
ANK repeat 585..610 CDD:293786 7/30 (23%)
ANK repeat 638..668 CDD:293786 7/45 (16%)
Ank_4 641..693 CDD:290365 10/73 (14%)
ANK 665..779 CDD:238125 21/141 (15%)
ANK repeat 672..703 CDD:293786 5/30 (17%)
Ank_2 677..769 CDD:289560 17/113 (15%)
ANK repeat 705..736 CDD:293786 7/52 (13%)
ANK repeat 738..769 CDD:293786 6/30 (20%)
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
ankrd55XP_001345419.4 Ank_2 25..117 CDD:289560 31/89 (35%)
ANK 50..208 CDD:238125 59/306 (19%)
ANK repeat 53..84 CDD:293786 14/30 (47%)
ANK repeat 86..152 CDD:293786 17/117 (15%)
ANKYR 91..344 CDD:223738 92/488 (19%)
ANK repeat 119..146 CDD:293786 7/47 (15%)
ANK 149..278 CDD:238125 54/302 (18%)
ANK repeat 154..185 CDD:293786 16/63 (25%)
ANK repeat 187..221 CDD:293786 13/120 (11%)
ANK repeat 223..288 CDD:293786 28/118 (24%)
ANK repeat 225..255 CDD:293786 11/81 (14%)
ANK 253..>310 CDD:238125 22/58 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1115202at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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