DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jigr1 and ubtfl

DIOPT Version :9

Sequence 1:	NP_001097920.1	Gene:	jigr1 / 43093	FlyBaseID:	FBgn0039350	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_957297.1	Gene:	ubtfl / 393978	ZFINID:	ZDB-GENE-040426-1159	Length:	719	Species:	Danio rerio

Alignment Length:	288	Identity:	55/288 - (19%)
Similarity:	105/288 - (36%)	Gaps:	97/288 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 NIEKRRVENGLSTQSSQWPLFESLQFLGDHIRPRRSF-KNMSVKEEDEETYEVDDCRSDSNGHMN 150
            |::..::   ||.:..:.|..:.|:::.:..|.:.|| |||:..:||               |.:
Zfish   141 NLDLTKI---LSKKYKELPEKKKLKYIQEFQREKESFEKNMARFKED---------------HPD 187

  Fly   151 SIKDELEDDSEIFDCEQALPVTTVLGIPLNNSDEANKSQRSTNGEMPNGKGYNHFAESYHRRHQN 215
            .|                              :|..||......:.|....|||..::|.:.|
Zfish   188 LI------------------------------EERKKSDLPEKPKTPQQLWYNHEKKTYMKIH-- 220

  Fly   216 QPEYIISSPIVNPMR------SNKRG----------SQHLDD--------HP---SKRRVDDSLS 253
             || :....:...:|      |:|:.          .:|.:|        ||   |:..|...|:
Zfish   221 -PE-VSQKELKEALRRQWSQLSDKKRLKWISKALELQKHYEDTMRAYIEAHPDANSEEHVKSVLT 283

  Fly   254 -----ISGYYPTQPLAPLPPAYAKFRGFGEFMCHSLCDMPAATALRLVQKFTRELVQSSLRNEDS 313
                 :...:..:|..|.|..|:.:  ..|.|. ::.|:|:...:.|..|..:.:.|   :.:|:
Zfish   284 KAERQLKDKFDGRPTKPPPNGYSLY--CAELMV-NMKDVPSTERMVLCSKQWKMMTQ---KEKDA 342

  Fly   314 -----GSKEKTDEVDPVDQSSESQEEDE 336
                 ..|:|..|:| :.:..||..::|
Zfish   343 FQKRCEQKKKQYEID-LQRFLESLPDEE 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jigr1	NP_001097920.1	MADF	33..118	CDD:214738	5/30 (17%)
ubtfl	NP_957297.1	HMGB-UBF_HMG-box	114..179	CDD:238686	10/40 (25%)
		HMGB-UBF_HMG-box	198..263	CDD:238686	13/68 (19%)
		HMGB-UBF_HMG-box	299..359	CDD:238686	15/66 (23%)
		HMG-box	433..509	CDD:294061
		HMGB-UBF_HMG-box	527..589	CDD:238686
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900