DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jigr1 and TOX3

DIOPT Version :9

Sequence 1:	NP_001097920.1	Gene:	jigr1 / 43093	FlyBaseID:	FBgn0039350	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001073899.2	Gene:	TOX3 / 27324	HGNCID:	11972	Length:	576	Species:	Homo sapiens

Alignment Length:	139	Identity:	34/139 - (24%)
Similarity:	51/139 - (36%)	Gaps:	32/139 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 NGKGYNHFAE-----------SYHRRHQNQPEYIISSPIVNPMRSNKRGSQHLDDHPSKRRVDDS 251
            |...|.:.||           ::|.......|:.| .||..|..|:          |:....|..
Human    32 NNNNYMNMAEANNAFFAASEQTFHTPSLGDEEFEI-PPITPPPESD----------PALGMPDVL 85

  Fly   252 LSISGYYPTQPLA-PLPPAYAKFRGFGEFMCHSLCDMPAATALRLVQKFTRELVQSSLRNEDSGS 315
            |      |.|.|: |||...::|.  .:|...|| |:|:.|..|.:.:....|..|.|..:.|.:
Human    86 L------PFQALSDPLPSQGSEFT--PQFPPQSL-DLPSITISRNLVEQDGVLHSSGLHMDQSHT 141

  Fly   316 KEKTDEVDP 324
            :......||
Human   142 QVSQYRQDP 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
jigr1	NP_001097920.1	MADF	33..118	CDD:214738
TOX3	NP_001073899.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	189..258
		HMG-box	255..320	CDD:238037
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	422..443
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	519..563
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900