DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jigr1 and Ubtf

DIOPT Version :9

Sequence 1:	NP_001097920.1	Gene:	jigr1 / 43093	FlyBaseID:	FBgn0039350	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001349473.1	Gene:	Ubtf / 21429	MGIID:	98512	Length:	764	Species:	Mus musculus

Alignment Length:	321	Identity:	67/321 - (20%)
Similarity:	116/321 - (36%)	Gaps:	104/321 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 VAHIWEQIAH--KLGYDATSIRERMTTLRNRYNIEKRRVENGLSTQSSQ-----WPLFESL---- 110
            :|.:|..::.  |..|.|   ||.....::.......|.:.|...:|.:     |.  :|:
Mouse   441 LARMWNDLSEKKKAKYKA---REAALKAQSERKPGGEREDRGKLPESPKRAEEIWQ--QSVIGDY 500

  Fly   111 --QFLGDHIRPRR----SFKNMSVKE---------EDEETYEVDDCRSDSNGHMNSIKDELEDDS 160
              :|..|.::..:    ::.||..||         ||::.||                   .:.|
Mouse   501 LARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYE-------------------RELS 546

  Fly   161 EIFDCEQALPVTTVLGIPLNNSDEANKSQRSTNGE--MPNGKGYNHFAESYHRRHQNQPEYIISS 223
            |:    :|.|..|       ||.:..|.|    ||  .|...||..|::.           ::|:
Mouse   547 EM----RAPPAAT-------NSSKKMKFQ----GEPKKPPMNGYQKFSQE-----------LLSN 585

  Fly   224 PIVN--PMRSN--------KRGSQHLDDHPSKRRVDDSLSISGYYP--TQPLAPLPPAYAKFRGF 276
            ..:|  |::..        :|.||...:|..|...:.......:..  .:.|:|...|     .:
Mouse   586 GELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQRQYKVHLDLWVKSLSPQDRA-----AY 645

  Fly   277 GEFMCHSLCDMPAATALRLVQ-KFTRELVQSSLRNEDSGSKEKTDEVDPVDQSSESQEEDE 336
            .|::.:...:|   |.||... |.:|..:||.     |.|:|..||.:..|:..|.:|:||
Mouse   646 KEYISNKRKNM---TKLRGPNPKSSRTTLQSK-----SESEEDDDEEEEDDEEEEEEEDDE 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jigr1	NP_001097920.1	MADF	33..118	CDD:214738	14/73 (19%)
Ubtf	NP_001349473.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		HMG_box	112..179	CDD:395407
		HMGB-UBF_HMG-box	196..261	CDD:238686
		HMGB-UBF_HMG-box	299..358	CDD:238686
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	370..411
		HMGB-UBF_HMG-box	407..470	CDD:238686	7/31 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	456..487		7/33 (21%)
		HMG_box_5	479..562	CDD:373364	21/114 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	546..576		13/44 (30%)
		HMGB-UBF_HMG-box	569..631	CDD:238686	12/72 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900