Protein Alignment Ssadh and ALD2

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_013893.1
• Gene: ALD2 / 855206
• SGDID: S000004780
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 490
• Identity: 173/490 - (35%)
• Similarity: 269/490 - (54%)
• Gaps: 22/490 - (4%)

  Fly    33 VDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLL 97
            ::..:..||:.| |.|..|||.|..|.........|..||:.||:.|::: .|...:::.|...|
Yeast    25 INNEFCPSSDGK-TIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDN-VWSKTSSEQRGIYL 87

  Fly    98 KKWHKLIEQHSQEIAEIMTAESGKPI-NESKGEVAYGNAFVEWFAEEARRI-YGEIVPSASPNRE 160
            ....||||:....:|.:.|.::|||. :.:||::|.......:||..|.:. .|..:| .:.|:.
Yeast    88 SNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIP-LTFNKF 151

  Fly   161 IIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKG 225
            ...:|.|.||.|.|.|||:|:||...|...|||||.||::||:|:|.|:.|..|.|...||.|.|
Yeast   152 AYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPG 216

  Fly   226 VINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSA-DGIKRICLELGGNAPFIVFDS 289
            |:|:| ....:.:|.......|:..|||||||:||..:...|. ..:|.:.||.||.:|.:||:.
Yeast   217 VVNIV-PGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFED 280

  Fly   290 ADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQG--------C 346
            ||::||:|...|..|.|.||.|.:.:|.:||.|:|||||.:.|:  .|.|..|..|        |
Yeast   281 ADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKE--TAKKEWDVAGKFDPFDEKC 343

  Fly   347 DVQIGPLINEMQFNKVSGFVE-DARSKKANIILGGQ-PLPDKGSLFYAPTIVTDVPPSAQLYSEE 409
            .|  ||:|:..|::::..::| ..|.:|.::....: |:......|..|||.||||.:::|..:|
Yeast   344 IV--GPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDE 406

  Fly   410 VFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAP 474
            :|||||.:.:|.:.::|:|.||||..|||...:::::::....|:.::.|.|.:|.........|
Yeast   407 IFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVP 471

  Fly   475 FGGVKESGVGREGSKHGIDDYVDIKYICMGNLKYD 509
            |||.|.||:|||..:.|:|.|:..|.:.: ||..|
Yeast   472 FGGFKMSGIGRELGQSGVDTYLQTKAVHI-NLSLD 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	165/466 (35%)
ALD2	NP_013893.1	ALDH_ALD2-YMR170C	14..502	CDD:143462	170/485 (35%)