Protein Alignment Ssadh and ALD4

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_015019.1
• Gene: ALD4 / 854556
• SGDID: S000005901
• Length: 519
• Species: Saccharomyces cerevisiae
• Alignment Length: 506
• Identity: 170/506 - (33%)
• Similarity: 277/506 - (54%)
• Gaps: 19/506 - (3%)

  Fly    11 TGSSLSLCRMRGFSALVQDKAL---------------VDGAWVDSSNAKATFEVRNPANGAVIGK 60
            :.||:...::|.||.|.....:               ::..:|.|...| ||||.||:....|..
Yeast    12 SASSIGRLQLRYFSHLPMTVPIKLPNGLEYEQPTGLFINNKFVPSKQNK-TFEVINPSTEEEICH 75

  Fly    61 VPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINE 125
            :......|.::|:.||.:|:.:..|..:...||...|.:..:||||....||.|.|.::||.|:.
Yeast    76 IYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISS 140

  Fly   126 SKGEVAYGNAFVEWFAEEARRIYGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGA 190
            |:|:|.....:::..|..|.:|.|.::.:...:.. ...:||:||...|.|||||:.|...|...
Yeast   141 SRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHFS-YTKRQPLGVCGQIIPWNFPLLMWAWKIAP 204

  Fly   191 ALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTG 255
            ||..|.|||:|.:|.|||:||.|:|....||||.||||:| :.....:|:.....|.::.::|||
Yeast   205 ALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIV-SGFGKIVGEAITNHPKIKKVAFTG 268

  Fly   256 STEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQ 320
            ||..|:.:::::|.|:|::.|||||.:|.|||..|:::|||...:...:.|.|:.|.:.:|.:|:
Yeast   269 STATGRHIYQSAAAGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVE 333

  Fly   321 DSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPD 385
            :|:||||:.:.|...|::|:||........|...::||.||:..:|:..:::.|.:|.||:.|..
Yeast   334 ESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGS 398

  Fly   386 KGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVF 450
            || .|..||:..||....::..||:|||||::.:|:..:|.:..|||:..|||...::.|:....
Yeast   399 KG-YFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTAL 462

  Fly   451 RVAKRLEVGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
            :||.|:..|.|.:|.........||||...||:|||.|...:.:|:.:|.:
Yeast   463 KVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAV 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	158/453 (35%)
ALD4	NP_015019.1	ALDH_F1-2_Ald2-like	42..514	CDD:143410	164/476 (34%)