DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ssadh and ALDH5F1

DIOPT Version :9

Sequence 1:	NP_001014665.1	Gene:	Ssadh / 43092	FlyBaseID:	FBgn0039349	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_178062.1	Gene:	ALDH5F1 / 844282	AraportID:	AT1G79440	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	257/504 - (50%)
Similarity:	355/504 - (70%)	Gaps:	10/504 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RQLSGVARTGSSLSLCRMRGFSALVQDKALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVA 67
            ||:|..|::.|.    ::|. |.|::.:.|:.|.|:||.:.| |.:|.|||.|.:|..|..|...
plant    32 RQMSMDAQSVSE----KLRS-SGLLRTQGLIGGKWLDSYDNK-TIKVNNPATGEIIADVACMGTK 90

  Fly    68 DAQKAIDAAKQAYESKEWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAY 132
            :...||.::.:|:.|  |..|||.:||.:|::|:.|:..|.:|:.:::|.|.|||:.|:.|||||
plant    91 ETNDAIASSYEAFTS--WSRLTAGERSKVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAY 153

  Fly   133 GNAFVEWFAEEARRIYGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCT 197
            |.:|:|::||||:|:||:|:|....:|.::|:|||:||...|||||||:||||||.|.|||:|||
plant   154 GASFIEYYAEEAKRVYGDIIPPNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCT 218

  Fly   198 VVVKPSEDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKL 262
            |||||||.|||||||.|:||:.||:|.|.:|||..| |..|||....||.||.|:|||||.|||.
plant   219 VVVKPSELTPLTALAAAELALQAGVPPGALNVVMGN-APEIGDALLTSPQVRKITFTGSTAVGKK 282

  Fly   263 LFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKF 327
            |...:|..:|::.||||||||.||||.||::.||.|.:|:||||.|||||.|||..|||.:||||
plant   283 LMAAAAPTVKKVSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKF 347

  Fly   328 VGQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYA 392
            .....:.|:.|::|||.......|||||:....||..||:||.||.|.||:||: ....|..||.
plant   348 AEAFSEAVQKLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGK-RHSLGMTFYE 411

  Fly   393 PTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLE 457
            ||::.||..:..:..||:||||..:|||:.||:|::.||||..|||.|.::.::|:.:||.:.||
plant   412 PTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRVFEALE 476

  Fly   458 VGMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYICMGNL 506
            .|:||||||:||...|||||||:||:||||||:|:|:|::|||:|:|::
plant   477 YGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYVCLGDM 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	240/453 (53%)
ALDH5F1	NP_178062.1	PLN02278	29..526	CDD:215157	257/504 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	484	1.000	Domainoid score	I84
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H840
Inparanoid	1	1.050	502	1.000	Inparanoid score	I313
OMA	1	1.010	-	-		QHG63174
OrthoDB	1	1.010	-	-		D899961at2759
OrthoFinder	1	1.000	-	-		FOG0003728
OrthoInspector	1	1.000	-	-		oto2808
orthoMCL	1	0.900	-	-		OOG6_102015
Panther	1	1.100	-	-	LDO	PTHR43353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2584
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840