DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ssadh and Aldh9a1

DIOPT Version :9

Sequence 1:	NP_001014665.1	Gene:	Ssadh / 43092	FlyBaseID:	FBgn0039349	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_071609.2	Gene:	Aldh9a1 / 64040	RGDID:	68409	Length:	497	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	166/482 - (34%)
Similarity:	258/482 - (53%)	Gaps:	16/482 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLKK 99
            ||.|:..:|..|.:...||.|..|.........:...|::.||.|:  |.|...:..:|..:|.:
  Rat    17 GARVEPVDASGTEKAFEPATGREIATFKCSGEKEVNLAVENAKAAF--KIWSKKSGLERCQVLLE 79

  Fly   100 WHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIV--PSASPNREII 162
            ..::|::...|||.:.|..:||.|.|::.:|......:|::|..|..:.||.:  |..|..   .
  Rat    80 AARIIKERRDEIAIMETINNGKSIFEARLDVDTSWQCLEYYAGLAASMAGEHIQLPGGSFG---Y 141

  Fly   163 VMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVI 227
            ..::|:||...|..||:|..:...|:..|||.|..::.|||..||::||.:|::...||.|.|:.
  Rat   142 TRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPNGLF 206

  Fly   228 NVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADI 292
            |||  ...|..|...|:..||..:|||||...|..:...:|.|||.|.|||||.:|.|:|...::
  Rat   207 NVV--QGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAAKGIKPITLELGGKSPLIIFSDCNM 269

  Fly   293 EKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEM 357
            :.||.||:.:.|...||.|.:..|.|||..:.|.|..::.::.:.:||||....|.::|||||..
  Rat   270 KNAVKGALLANFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPLLEDTRMGPLINAP 334

  Fly   358 QFNKVSGFVEDARSKKANIILGGQP-LPD----KGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSI 417
            ...:|.|||..|:.:.|.::.||:| .|:    |...:..|.|:|:.........||:||||:||
  Rat   335 HLERVLGFVRSAKEQGATVLCGGEPYAPEDPKLKHGYYMTPCILTNCTDDMTCVKEEIFGPVMSI 399

  Fly   418 IRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESG 482
            :.|..|.|.:::||||..|||...::.::|:..|||..|:.|...:|...:|..|.||||.|:||
  Rat   400 LTFETEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSG 464

  Fly   483 VGREGSKHGIDDYVDIKYIC--MGNLK 507
            .|||..:..|:.|..:|.:|  ||:::
  Rat   465 FGRENGRVTIEYYSQLKTVCVEMGDVE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	159/462 (34%)
Aldh9a1	NP_071609.2	ALDH_F9_TMBADH	31..488	CDD:143409	159/463 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810