DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ssadh and aldh9a1b

DIOPT Version :9

Sequence 1:	NP_001014665.1	Gene:	Ssadh / 43092	FlyBaseID:	FBgn0039349	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	XP_009295330.1	Gene:	aldh9a1b / 399481	ZFINID:	ZDB-GENE-040120-5	Length:	539	Species:	Danio rerio

Alignment Length:	482	Identity:	161/482 - (33%)
Similarity:	269/482 - (55%)	Gaps:	17/482 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GAWVDSSNAKATFE-VRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLK 98
            ||.||..:.|...| |..||.|.|:.::.....|:...|:..|..|:  |.||.|:..:|:.::.
Zfish    61 GARVDLKDVKTKSEPVFEPATGRVLCRLQTCGSAEVDAAVRNASAAF--KVWRKLSGMERARVML 123

  Fly    99 KWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIV--PSASPNREI 161
            :..:|||:..:||||:....:||.|.|::.:|......:|:||.:|..:.|:.|  |..|   ..
Zfish   124 EAARLIEKRREEIAEMEVINNGKSITEARLDVDSARLSIEYFAGQATTLSGQHVQLPGGS---FA 185

  Fly   162 IVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGV 226
            ...::|.||...|..||:|..:...|:..|:|.|.::|.|||..||:||:.:|::...||.|:|:
Zfish   186 YTRREPFGVCVGIGAWNYPFQIAAWKSAPAIACGNSMVFKPSPLTPVTAVLLAEIYRQAGAPEGL 250

  Fly   227 INVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSAD 291
            .|||...:..  |.|.|..|.|..:|||||...||.:...::.|:|.:.|||||.:|.|:|:..|
Zfish   251 FNVVQGGQET--GSLLCLHPSVEKVSFTGSVPTGKKIMEMASRGVKAVTLELGGKSPLIIFEDTD 313

  Fly   292 IEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINE 356
            :|.||.||:.:.|.:.||.|.:..|.|||.|:..:|:.::.:|.:|:.|||....:.::|.|:::
Zfish   314 LENAVRGALMANFLSQGQVCSNGTRVFVQSSIVPQFLKEVVRRTKAISIGDPLLDETRMGALVSK 378

  Fly   357 MQFNKVSGFVEDARSKKANIILGGQPLPD-----KGSLFYAPTIVTDVPPSAQLYSEEVFGPVVS 416
            ...:||..:||.|:::.|.::.||:|...     |...:..|.::...........||:||||:|
Zfish   379 AHLDKVLRYVEQAKNEGAQVLCGGEPFSPADPKLKDGYYMTPCVLDSCTDDMTCVKEEIFGPVMS 443

  Fly   417 IIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKES 481
            ::.|..|:|.:::|||:..|||...:::::::..||.:.|:.|...:|...|:..|.||||.|.|
Zfish   444 VLTFDTEDEVLRRANDSDLGLAAGVFTKDVKRAHRVIENLQAGSCFINNYNITPVEVPFGGFKAS 508

  Fly   482 GVGREGSKHGIDDYVDIKYIC--MGNL 506
            |:|||..:..|:.|..:|.:.  ||::
Zfish   509 GIGRENGQVTIEFYSQLKTVVVEMGDV 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	153/462 (33%)
aldh9a1b	XP_009295330.1	ALDH_F9_TMBADH	76..533	CDD:143409	153/463 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810