Protein Alignment Ssadh and aldh2.1

DIOPT Version :9

• Sequence 1: NP_001014665.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_956784.1
• Gene: aldh2.1 / 393462
• ZFINID: ZDB-GENE-040426-1262
• Length: 516
• Species: Danio rerio
• Alignment Length: 485
• Identity: 173/485 - (35%)
• Similarity: 270/485 - (55%)
• Gaps: 25/485 - (5%)

  Fly    29 DKALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYE-SKEWRSLTAKD 92
            :|..::..|.|:. :|.||...|||...||..|.....||..||:.||:.|:: ...||.:.|..
Zfish    36 NKIFINNEWHDAV-SKKTFPTINPATAEVICHVAEGDKADVDKAVKAARDAFKLGSPWRRMDASQ 99

  Fly    93 RSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAF----------VEWFAEEARRI 147
            |..||.:....||:.:..:||:.|.::|||         |..:|          :.::|..|.:.
Zfish   100 RGLLLNRLADCIERDAAYLAELETLDNGKP---------YTLSFCVDLPMVVKCLRYYAGWADKW 155

  Fly   148 YGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALA 212
            .|:.:| ...|.......:||||...|.|||||:.|...|.|.|||.|.|||:|.:|.||||||.
Zfish   156 EGKTIP-IDGNYFCYTRHEPIGVCGQIIPWNFPLLMQALKLGPALATGNTVVMKVAEQTPLTALY 219

  Fly   213 VAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFR-NSADGIKRICL 276
            :|.|..:.|.|.||:|:| .......|.......||..::|||||:||.|:.: :||..:|.:.|
Zfish   220 IASLIKEVGFPAGVVNIV-PGFGPTAGAAIASHMDVDKVAFTGSTDVGHLIQQASSASNLKNVSL 283

  Fly   277 ELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIG 341
            ||||.:|.|:...|::|:||:.|.::.|.|.||.|.:..|.|||:|:||:||.:..:|.:...:|
Zfish   284 ELGGKSPNIILSDANMEEAVEQAHSALFFNQGQCCCAGTRTFVQESIYDEFVERSVERAKNRIVG 348

  Fly   342 DGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLY 406
            |....:.:.||.::|.||.||.|::...:.:.|.::.||.|..::| .|..||:..||.....:.
Zfish   349 DPFDLNTEQGPQVDEDQFKKVLGYISSGKREGAKLMCGGAPAAERG-YFIQPTVFGDVKDDMTIA 412

  Fly   407 SEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAA 471
            .||:||||:.|::|:..||.:::|||::.|||...:::|:.:...::..|..|.|.:|...:...
Zfish   413 REEIFGPVMQILKFKSLEEVIERANDSKYGLAAAVFTQNIDKANYISHGLRAGTVWINCYNVFGV 477

  Fly   472 EAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
            :|||||.|.||:|||..::|:|.|.::|.:
Zfish   478 QAPFGGYKASGIGRELGEYGLDIYTEVKTV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	167/465 (36%)
aldh2.1	NP_956784.1	ALDH_F1AB_F2_RALDH1	30..510	CDD:143459	173/485 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810