Protein Alignment Ssadh and Aldh1l2

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001178707.2
• Gene: Aldh1l2 / 299699
• RGDID: 1309458
• Length: 923
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 160/490 - (32%)
• Similarity: 274/490 - (55%)
• Gaps: 28/490 - (5%)

  Fly    30 KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRS 94
            :..::|.:||:.:.: |:...||.:|..:.:|...::||..:|:.|||.|:|:.||..:.|:||.
  Rat   444 QCFINGQFVDAEDGE-TYATINPTDGTTLCRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRG 507

  Fly    95 NLLKKWHKLIEQHSQEIAEIMTAESGKPINES-KGEVAYGNAFVEWFA------------EEARR 146
            .|:.:...|:|::.:|:|.|...:||.....: |..:........:||            |...|
  Rat   508 RLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQVTKEPENQAR 572

  Fly   147 IYGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTAL 211
            |:..:..|:         ::|..|.|:|.|||:|:.|:..|:.|.||||.|:|:||::.||||||
  Rat   573 IHDTLGMSS---------EEPKVVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTAL 628

  Fly   212 AVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSA-DGIKRIC 275
            ..|:|.|.||.||||||:: .......|....:.||:|.:.|||||.|||.:.::.| ..:|::.
  Rat   629 KFAELTVKAGFPKGVINII-PGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVS 692

  Fly   276 LELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKI 340
            |||||.:|.|:|...:::|||...|.:.|.|.|:.|::|.|.||:::::|:||.::.:.::.:||
  Rat   693 LELGGKSPLIIFSDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKMKI 757

  Fly   341 GDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQL 405
            ||........||..::....|:..:.|....:.|.::.||:.:...| .|..||:.|.|.....|
  Rat   758 GDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPG-FFMEPTVFTGVEDHMYL 821

  Fly   406 YSEEVFGPVVSIIRFR--DEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGII 468
            ..||.|||::.|.:|:  |.:..:::||:|..|||...::.::.:...|:.|||.|.|.:|....
  Rat   822 AKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDISKAMYVSDRLEAGTVFINTYNK 886

  Fly   469 SAAEAPFGGVKESGVGREGSKHGIDDYVDIKYICM 503
            :...|||||||:||.|::..:..:::|:..|.:.:
  Rat   887 TDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTL 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	156/469 (33%)
Aldh1l2	NP_001178707.2	FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..>390	CDD:425746
		ALDH_F1L_FTFDH	438..923	CDD:143458	160/490 (33%)